This is a synthetic peptide designed for use in combination with anti-Noto Antibody(ARP36811_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
NOTO
(Notochord Homeobox (NOTO))
Synonyme
Xnot-2 Peptide, Xnot2 Peptide, not Peptide, nota Peptide, noto Peptide, RGD1562910 Peptide, Xnot Peptide, Flh Peptide, MmNot Peptide, Not Peptide, tc Peptide, Znot Peptide, flh Peptide, notochord homeobox Peptide, notochord homeobox S homeolog Peptide, NOTO Peptide, not.S Peptide, Noto Peptide, not Peptide, noto Peptide
Hintergrund
Noto is a transcription regulator acting downstream of both FOXA2 and T during notochord development.Noto is required for node morphogenesis.Noto is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.