Notochord Homeobox (NOTO) (C-Term) Peptid
NOTO
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle NOTO Produkte
- NOTO (Notochord Homeobox (NOTO))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- CSGLWAFPDW APTEDLQDTE RQQKRVRTMF NLEQLEELEK VFAKQHNLVG
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NOTO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NOTO (Notochord Homeobox (NOTO))
- Synonyme
- Xnot-2 Peptide, Xnot2 Peptide, not Peptide, nota Peptide, noto Peptide, RGD1562910 Peptide, Xnot Peptide, Flh Peptide, MmNot Peptide, Not Peptide, tc Peptide, Znot Peptide, flh Peptide, notochord homeobox Peptide, notochord homeobox S homeolog Peptide, NOTO Peptide, not.S Peptide, Noto Peptide, not Peptide, noto Peptide
- Hintergrund
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NOTO is a transcription regulator acting downstream of both FOXA2 and T during notochord development. It is required for node morphogenesis. It is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, it acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. And it plays a role in regulating axial versus paraxial cell fate (By similarity).
Alias Symbols: NOTO,
Protein Size: 251 - Gen-ID
- 344022
- NCBI Accession
- NP_001127934
- UniProt
- A8MTQ0
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