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F-Box and WD Repeat Domain Containing 8 (FBXW8) (Middle Region) Peptid

FBXW8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976773
  • Target Alle FBXW8 Produkte
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-FBXW8 Antibody(ARP55586_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    Synonyme
    FBW6 Peptide, FBW8 Peptide, FBX29 Peptide, FBXO29 Peptide, FBXW6 Peptide, 4930438M06Rik Peptide, Fbx29 Peptide, F-box and WD repeat domain containing 8 Peptide, ring finger protein, transmembrane 2 Peptide, F-box and WD-40 domain protein 8 Peptide, FBXW8 Peptide, Fbxw8 Peptide, RNFT2 Peptide
    Hintergrund
    FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.

    Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6

    Protein Interaction Partner: SKP1,CUL7,RBX1,SKP1,CUL7,EP300,RBX1,SKP1

    Protein Size: 598
    Molekulargewicht
    67 kDa
    Gen-ID
    26259
    NCBI Accession
    NM_153348, NP_699179
    UniProt
    Q8N3Y1
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