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FBXW8 Produkte

(F-Box and WD Repeat Domain Containing 8 (FBXW8))
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte FBXW8 Kategorien

FBXW8 Antikörper

High quality antibodies with extensive validation data.

FBXW8 ELISA Kits

Reliable ELISA kits for a wide range of species.

FBXW8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FBXW8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN654676
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN565252
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), EIA
Validierungen
  • (4)
Kat. Nr. ABIN952296
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene FBXW8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1745579
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1744360
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Monkey
Analytical Method
Validierungen
Kat. Nr. ABIN1770372
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FBXW8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353882
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3092555
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136178
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FBXW8 Produkten

Halbach, Stehning, Damrath, Jendrach, Şen, Başak, Auburger: "Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121089, (2015) (PubMed).

Wang, Chen, Lin, Li, Zhou, Liu, Logsdon, Jin, Abbruzzese, Tan, Wang: "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1." in: The Journal of biological chemistry, Vol. 289, Issue 7, pp. 4009-17, (2014) (PubMed).

Achiwa, Hasegawa, Udagawa: "Effect of ursolic acid on MAPK in cyclin D1 signaling and RING-type E3 ligase (SCF E3s) in two endometrial cancer cell lines." in: Nutrition and cancer, Vol. 65, Issue 7, pp. 1026-33, (2013) (PubMed).

Fahlbusch, Dawood, Hartner, Menendez-Castro, Nögel, Tzschoppe, Schneider, Strissel, Beckmann, Schleussner, Ruebner, Dörr, Schild, Rascher, Dötsch: "Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?" in: The journal of maternal-fetal & neonatal medicine, Vol. 25, Issue 11, pp. 2209-15, (2012) (PubMed).

Lin, Fu, Zhao, Lin, Zou, Liu, Zhu, Wang, Yu: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." in: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).

Wei, Yang, Chuang, Yang, Kulp, Lu, Lai, Chen: "A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26759-70, (2008) (PubMed).

Synonyme und alternative Namen zu FBXW8

F-box and WD repeat domain containing 8 (FBXW8), F-box and WD repeat domain containing 8 (Fbxw8), ring finger protein, transmembrane 2 (RNFT2), F-box and WD-40 domain protein 8 (Fbxw8), 4930438M06Rik, FBW6, FBW8, FBX29, Fbx29, FBXO29, FBXW6

Bezeichner auf Proteinebene für FBXW8

  • F-box and WD-40 domain protein 8
  • F-box and WD-40 domain-containing protein 8
  • F-box only protein 29
  • F-box/WD repeat-containing protein 8
  • F-box protein FBX29
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