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FCAR Produkte

(Fc Fragment of IgA, Receptor For (FCAR))

Kategorien

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte FCAR Kategorien

FCAR Antikörper

High quality antibodies with extensive validation data.

FCAR ELISA Kits

Reliable ELISA kits for a wide range of species.

FCAR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FCAR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, FACS, ICC, IHC, Neut, WB
Validierungen
  • (4)
Kat. Nr. ABIN5684138
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC (p), WB
Validierungen
  • (2)
Kat. Nr. ABIN3181421
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (p), WB
Validierungen
  • (2)
Kat. Nr. ABIN2855990
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FCAR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955737
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882811
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951593
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FCAR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3080091
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3080090
Menge 0.5 mg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2713806
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FCAR Produkten

Björklund, Carlsten, Sohlberg, Liu, Clancy, Karimi, Cooley, Miller, Klimkowska, Schaffer, Watz, Wikström, Blomberg, Wahlin, Palma, Hansson, Ljungman, Hellström-Lindberg, Ljunggren, Malmberg: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).

Moresco, Speeckaert, Zmonarski, Krajewska, Komuda-Leszek, Perkowska-Ptasinska, Gesualdo, Rocchetti, Delanghe, Vanholder, Van Biesen, Delanghe: "Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis." in: BBA clinical, Vol. 5, pp. 79-84, (2016) (PubMed).

Matt, Lindqvist, Kleinau: "Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc?R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137474, (2015) (PubMed).

Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).

Duc, Johansen, Corthésy: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).

Yin, Peng, Xing, Zhang: "Intracellular pools of FcalphaR (CD89) in human neutrophils are localized in tertiary granules and secretory vesicles, and two FcalphaR isoforms are found in tertiary granules." in: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 551-8, (2007) (PubMed).

Zhang, Bi, Oldroyd, Lachmann: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." in: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).

Monteiro, Cooper, Kubagawa: "Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 6, pp. 1764-70, (1992) (PubMed).

Synonyme und alternative Namen zu FCAR

Fc fragment of IgA receptor (FCAR), Fc fragment of IgA, receptor for (FCAR), CD89

Bezeichner auf Proteinebene für FCAR

  • IgA Fc receptor
  • immunoglobulin A Fc receptor
  • immunoglobulin alpha Fc receptor
  • Fc fragment of IgA, receptor for, isoform 7
  • Fc alpha receptor
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