FCAR Protein (AA 22-227) (His tag)
-
- Target Alle FCAR Proteine anzeigen
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 22-227
-
Spezies
- Human
-
Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses FCAR Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH
- Reinheit
- > 85 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FCAR Protein
-
Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)
FCAR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgA, Receptor For (FCAR) (AA 24-133) protein (GST tag)FCAR Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Fc Fragment of IgA, Receptor For (FCAR) protein (His tag)FCAR Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) protein (His tag)Crystallography grade FCAR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgA, Receptor For (FCAR) (AA 22-287) protein (rho-1D4 tag)Crystallography grade FCAR Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Andere Bezeichnung
- FCAR (FCAR Produkte)
- Synonyme
- CD89 Protein, Fc fragment of IgA receptor Protein, Fc fragment of IgA, receptor for Protein, FCAR Protein
- Hintergrund
- FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. Recombinant human FCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 24.5kDa (215aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001991
- UniProt
- P24071
-
