Fc Receptor, IgG, Low Affinity IV Produkte
(Fc Receptor, IgG, Low Affinity IV (FCGR4))
Kategorien
Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.
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Ausgewählte Fc Receptor, IgG, Low Affinity IV Kategorien
Fc Receptor, IgG, Low Affinity IV Antikörper
High quality antibodies with extensive validation data.
Fc Receptor, IgG, Low Affinity IV Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Fc Receptor, IgG, Low Affinity IV Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
FACS
Validierungen
- (1)
Kat. Nr.
ABIN2664272
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Fc Receptor, IgG, Low Affinity IV ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730047
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Fc Receptor, IgG, Low Affinity IV Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Human Cells
Validierungen
Kat. Nr.
ABIN7314672
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Fc Receptor, IgG, Low Affinity IV Produkten
: "Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma." in: Journal for immunotherapy of cancer, Vol. 4, pp. 28, (2016) (PubMed).: "Interaction with Fc?RIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 4, pp. 1754-63, (2011) (PubMed).
Synonyme und alternative Namen zu Fc Receptor, IgG, Low Affinity IV
Fc receptor, IgG, low affinity IV (Fcgr4), 4833442P21Rik, CD16-2, FcgammaRIV, Fcgr3a, FcgRIV, Fcrl3Bezeichner auf Proteinebene für Fc Receptor, IgG, Low Affinity IV
- CD16-2
- Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16)
- Fc gammaRIV
- Fc receptor-like 3
- FcgammaRIV
- low affinity immunoglobulin gamma Fc region receptor III-A
- low affinity immunoglobulin gamma Fc region receptor IV
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