This is a synthetic peptide designed for use in combination with anti-AGTR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
Angiotensin II Type 2 Receptor (AGTR2)
(Angiotensin II Receptor, Type 2 (AGTR2))
Synonyme
AT2 Peptide, ATGR2 Peptide, MRX88 Peptide, AI316812 Peptide, AW107640 Peptide, AT2-R Peptide, AT2R Peptide, AT2R Peptide, at2 Peptide, zgc:113016 Peptide, AGTR2 Peptide, angiotensin II receptor type 2 Peptide, angiotensin II receptor, type 2 Peptide, AGTR2 Peptide, Agtr2 Peptide, agtr2 Peptide
Hintergrund
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
Alias Symbols: AT2, ATGR2, MRX88
Protein Interaction Partner: ACE,AGT,ERBB3,GNAI2,GNAI3,MTUS1,PIK3CB,ZBTB16,AGTRAP,MTUS1