Angiotensin II Type 2 Receptor (AGTR2)
(Angiotensin II Receptor, Type 2 (AGTR2))
Protein-Typ
Synthetic
Spezies
Hormone
Quelle
Synthetic
Applikation
Blocking Peptide (BP), ELISA
Kreuzreaktivität (Details)
This 18 AA human immunogenic peptide is 100 % homologous in rabbit, 88 % identical in rat and 83 % with mouse AT2 receptors. It has no sequence homology with AtII type 1 or other G-protein coupled receptors.
Produktmerkmale
A synthetic AT2 Blocking peptide for use as a blocking control in assays to test for specificity of AT2 antibody, Alternative Names: AT2 Blocking peptide, Angiotensin II Blocking peptide, AT-2 Blocking peptide, AT2 Control peptide, Angiotensin II Blocking peptide, AT-2 Blocking peptide, AT2 Control peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 100 µL of PBS.
Buffer
Lyophilized from PBS, pH 7.5, with 0.05 % NaN3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
Angiotensin II Type 2 Receptor (AGTR2)
(Angiotensin II Receptor, Type 2 (AGTR2))
Synonyme
AT2 Peptide, ATGR2 Peptide, MRX88 Peptide, AI316812 Peptide, AW107640 Peptide, AT2-R Peptide, AT2R Peptide, AT2R Peptide, at2 Peptide, zgc:113016 Peptide, AGTR2 Peptide, angiotensin II receptor type 2 Peptide, angiotensin II receptor, type 2 Peptide, AGTR2 Peptide, Agtr2 Peptide, agtr2 Peptide
Hintergrund
Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G protein-coupled receptors. It is an integral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system.