A synthetic peptide for use as a blocking control in assays to test for specificity of ABCD4 antibody, Alternative Names: ABCD4 control peptide, ABCD4 antibody Blocking Peptide, Anti-ABCD4 Blocking Peptide, Atp-Binding Cassette Sub-Family D4 Blocking Peptide, Ald4 Blocking Peptide, ABC41 Blocking Peptide, EST352188 Blocking Peptide, P70R Blocking Peptide, P79R Blocking Peptide, PMP69 Blocking Peptide, PXMP1L Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ABCD4
(ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))
Synonyme
ABC41 Peptide, EST352188 Peptide, MAHCJ Peptide, P70R Peptide, P79R Peptide, PMP69 Peptide, PXMP1L Peptide, Pxmp1l Peptide, ABCD4 Peptide, zgc:153503 Peptide, P69r Peptide, ATP binding cassette subfamily D member 4 Peptide, ATP-binding cassette, sub-family D (ALD), member 4 Peptide, ABCD4 Peptide, Abcd4 Peptide, abcd4 Peptide
Hintergrund
ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.