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ABCD4 Produkte

(ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))

Kategorien

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008].

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Ausgewählte ABCD4 Kategorien

ABCD4 Antikörper

High quality antibodies with extensive validation data.

ABCD4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ABCD4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, ICC, IF
Validierungen
  • (3)
Kat. Nr. ABIN6257921
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN335110
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC
Validierungen
  • (4)
Kat. Nr. ABIN5013197
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ABCD4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3109592
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3132293
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN6239310
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ABCD4 Produkten

Coelho, Kim, Miousse, Fung, du Moulin, Buers, Suormala, Burda, Frapolli, Stucki, Nürnberg, Thiele, Robenek, Höhne, Longo, Pasquali, Mengel, Watkins, Shoubridge, Majewski, Rosenblatt, Fowler, Rutsch et al.: "Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. ..." in: Nature genetics, Vol. 44, Issue 10, pp. 1152-5, (2012) (PubMed).

Asheuer, Bieche, Laurendeau, Moser, Hainque, Vidaud, Aubourg: "Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy." in: Human molecular genetics, Vol. 14, Issue 10, pp. 1293-303, (2005) (PubMed).

Synonyme und alternative Namen zu ABCD4

ATP binding cassette subfamily D member 4 (ABCD4), ATP binding cassette subfamily D member 4 (Abcd4), ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), ATP-binding cassette, sub-family D (ALD), member 4 (abcd4), ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4), ABC41, ABCD4, EST352188, MAHCJ, P69r, P70R, P79R, PMP69, PXMP1L, Pxmp1l, zgc:153503

Bezeichner auf Proteinebene für ABCD4

  • 69 kDa peroxisomal ABC-transporter
  • ATP-binding cassette sub-family D member 4
  • PMP70-related protein
  • PXMP1-L
  • peroxisomal membrane protein 69
  • ATP-binding cassette, sub-family D (ALD), member 4
  • ATP-binding cassette, sub-family D, member 4
  • PMP69
  • peroxisomal membrane protein, 70 kDa-related
  • ATP-binding cassette sub-family D member 4-like
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