ABCG2 Produkte
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
Kategorien
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
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Ausgewählte ABCG2 Kategorien
ABCG2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene ABCG2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, IF, FACS
Validierungen
- (6)
Kat. Nr.
ABIN3030062
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN388306
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN7328483
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene ABCG2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7283960
Menge
200 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7392836
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7392833
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ABCG2 Produkten
: "Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats." in: Molecular neurobiology, Vol. 56, Issue 3, pp. 1921-1932, (2019) (PubMed).: "Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma." in: BMC cancer, Vol. 17, Issue 1, pp. 156, (2018) (PubMed).
: "Localization of the placental BCRP/ABCG2 transporter to lipid rafts: Role for cholesterol in mediating efflux activity." in: Placenta, Vol. 55, pp. 29-36, (2018) (PubMed).
: "Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells." in: Oncology letters, Vol. 15, Issue 1, pp. 1255-1262, (2018) (PubMed).
: "Cariprazine, A Dopamine D₂/D₃ Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).
: "Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol." in: Scientific reports, Vol. 8, Issue 1, pp. 587, (2018) (PubMed).
: "Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway." in: Biomedicine & pharmacotherapy, Vol. 107, pp. 793-805, (2018) (PubMed).
: "The dopamine D3 receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines." in: Cancer letters, Vol. 396, pp. 167-180, (2017) (PubMed).
: "Neurorescue by a ROS Decomposition Catalyst." in: ACS chemical neuroscience, Vol. 7, Issue 10, pp. 1374-1382, (2016) (PubMed).
: "Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors." in: Molecular pharmaceutics, Vol. 13, Issue 7, pp. 2507-23, (2016) (PubMed).
Synonyme und alternative Namen zu ABCG2
ATP binding cassette subfamily G member 2 (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) (abcg2), ATP binding cassette subfamily G member 2 (Junior blood group) (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog (abcg2.L), ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) (Abcg2), ATP-binding cassette sub-family G member 2 (LOC100008640), ATP binding cassette subfamily G member 2 (Abcg2), ABC15, ABCG2, ABCG3, ABCP, AI428558, bcrp, BCRP, BCRP1, Bcrp1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1Bezeichner auf Proteinebene für ABCG2
- ATP-binding cassette, sub-family G, member 2
- breast cancer resistance protein
- ATP-binding cassette sub-family G member 2
- ATP-binding cassette transporter subfamily G member 2
- ATP-binding cassette, sub-family G (WHITE), member 2
- ATP-binding cassette sub-family G member 2-like
- ABC transporter
- ATP-binding cassette transporter G2
- mitoxantrone resistance-associated protein
- multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2
- placenta specific MDR protein
- placenta-specific ATP-binding cassette transporter
- ATP-binding cassette protein G2
- brain multidrug resistance protein
- ATP binding cassette superfamily G number 2 transporter
- breast cancer resistance protein 1 homolog
- mitoxantrone resistance protein 1
- ATP-binding cassette transporter sub-family G member 2
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