Abcd2 Produkte
(ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))
Kategorien
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown\; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008].
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Ausgewählte Abcd2 Kategorien
Abcd2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene Abcd2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, ICC, IP
Validierungen
- (5)
Kat. Nr.
ABIN7445003
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN467567
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN2854625
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Abcd2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6224893
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Abcd2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7419502
Menge
100 μg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu Abcd2
ATP binding cassette subfamily D member 2 (ABCD2), ABC transporter D family protein (abcD2), ATP-binding cassette sub-family D member 2 (LOC100549247), ATP binding cassette subfamily D member 2 (abcd2), ATP-binding cassette sub-family D member 2 (LOC100640478), ATP-binding cassette, sub-family D (ALD), member 2 (Abcd2), ATP binding cassette subfamily D member 2 (Abcd2), ABC39, ALDL1, ALDR, ALDRP, DDBDRAFT_0214891, DDBDRAFT_0219834, DDB_0214891, DDB_0219834, hALDRBezeichner auf Proteinebene für Abcd2
- ATP-binding cassette, sub-family D, member 2
- ATP-binding cassette, sub-family D (ALD), member 2
- ATP-binding cassette sub-family D member 2
- ATP-binding cassette sub-family D member 2-like
- adrenoleukodystrophy-like 1
- adrenoleukodystrophy-related protein
- adrenoleukodystrophy related
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