Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (N-Term) Peptid
PTPN11
Reaktivität: Human
Wirt: Synthetic
WB
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- Target Alle PTPN11 Produkte
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Western Blotting (WB)
- Sequenz
- KSNPGDFTLS VRRNGAVTHI KIQNTGDYYD LYGGEKFATL AELVQYYMEH
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PTN11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
- Synonyme
- BPTP3 Peptide, CFC Peptide, NS1 Peptide, PTP-1D Peptide, PTP2C Peptide, SH-PTP2 Peptide, SH-PTP3 Peptide, SHP2 Peptide, 2700084A17Rik Peptide, AW536184 Peptide, PTP1D Peptide, SAP-2 Peptide, SHP-2 Peptide, Shp2 Peptide, Syp Peptide, SYP Peptide, bptp3 Peptide, cfc Peptide, ns1 Peptide, ptp-2 Peptide, ptp2c Peptide, ptpn11 Peptide, ptpn11-a Peptide, ptpn11-b Peptide, shp-2 Peptide, shp2 Peptide, fa14b09 Peptide, wu:fa14b09 Peptide, wu:fi24f03 Peptide, zgc:55388 Peptide, zgc:63553 Peptide, protein tyrosine phosphatase, non-receptor type 11 Peptide, protein tyrosine phosphatase, non-receptor type 11 S homeolog Peptide, protein tyrosine phosphatase, non-receptor type 11, a Peptide, protein tyrosine phosphatase, non-receptor type 11, b Peptide, PTPN11 Peptide, Ptpn11 Peptide, ptpn11.S Peptide, ptpn11a Peptide, ptpn11b Peptide
- Hintergrund
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PTPN11,PTP2C, SHPTP2,
Protein Size: 597 - Gen-ID
- 5781
- NCBI Accession
- XP_006719589
- UniProt
- Q06124
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