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Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (Middle Region) Peptid

MTHFD1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512779
  • Target Alle MTHFD1 Produkte
    MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    EWIKPGAIVI DCGINYVPDD KKPNGRKVVG DVAYDEAKER ASFITPVPGG
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-MTHFD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
    Synonyme
    MTHFC Peptide, MTHFD Peptide, Tb07.27M11.970 Peptide, Dcs Peptide, E430024A07Rik Peptide, Mthfd Peptide, GB13160 Peptide, cb325 Peptide, fc29f07 Peptide, mthfd1 Peptide, wu:fc29f07 Peptide, zgc:55597 Peptide, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Peptide, C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase,cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Peptide, c-1-tetrahydrofolate synthase, cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Peptide, MTHFD1 Peptide, Mthfd1 Peptide, Tc00.1047053509509.20 Peptide, Tc00.1047053511741.50 Peptide, Tc00.1047053511517.60 Peptide, Tc00.1047053508207.240 Peptide, Tb927.7.1600 Peptide, LINJ_26_0310 Peptide, LBRM_26_0350 Peptide, LMJF_26_0320 Peptide, mthfd1l Peptide, LOC550749 Peptide, mthfd1b Peptide, Tsp_00651 Peptide, mthfd1.L Peptide, mthfd1 Peptide, LOC589933 Peptide, LOC100634307 Peptide
    Hintergrund
    This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

    Alias Symbols: MTHFC, MTHFD

    Protein Size: 935
    Gen-ID
    4522
    NCBI Accession
    NM_005956, NP_005947
    UniProt
    P11586
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