Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (Middle Region) Peptid
CAND1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CAND1 Produkte
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- YNYDDEDEDE NAMDADGGDD DDQGSDDEYS DDDDMSWKVR RAAAKCLDAV
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CAND1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- Synonyme
- TIP120 Peptide, TIP120A Peptide, ATCAND1 Peptide, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 Peptide, ETA2 Peptide, HEMIVENATA Peptide, HVE Peptide, T8K22.14 Peptide, T8K22_14 Peptide, cullin-associated and neddylation dissociated Peptide, Tip120 Peptide, Tip120A Peptide, fb78a05 Peptide, wu:fb78a05 Peptide, zgc:55729 Peptide, tip120 Peptide, tip120a Peptide, cand2 Peptide, 2310038O07Rik Peptide, 6330512O03Rik Peptide, AI195005 Peptide, AI846556 Peptide, D10Ertd516e Peptide, Tp120a Peptide, mKIAA0829 Peptide, cullin associated and neddylation dissociated 1 Peptide, cullin-associated and neddylation dissociated Peptide, cullin-associated and neddylation-dissociated 1 Peptide, cullin-associated and neddylation-dissociated 1 L homeolog Peptide, cullin-associated NEDD8-dissociated protein 1 Peptide, cullin associated and neddylation disassociated 1 Peptide, CAND1 Peptide, Cand1 Peptide, cand1 Peptide, cand1.L Peptide, LOC100159824 Peptide, LOC100177977 Peptide
- Hintergrund
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Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.
Alias Symbols: TIP120, TIP120A
Protein Size: 1062 - Gen-ID
- 55832
- NCBI Accession
- NM_018448, NP_060918
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