CAND1
(Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-CAND1 antibody (Catalog #: ARP34584_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.
Alias Symbols: DKFZp434M1414, FLJ10114, FLJ10929, FLJ38691, FLJ90441, KIAA0829, TIP120, TIP120A
Protein Interaction Partner: CNOT3,CUL1,CUL2,CUL3,CUL4A,CUL4B,RBX1,BRCC3,CAND1,CUL1,CUL2,CUL3,CUL4A,CUL4B,DCUN1D1,MEPCE,RBX1,TCEA2