anti-Meerschweinchen PCSK1 Antikörper für Western Blotting
Recommended PCSK1 Antibody (geliefert von: Anmelden zum Anzeigen )
- Antigen
-
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) Antikörper
Synonyme für dieses Antigen anzeigen- BMIQ12
- NEC1
- PC1
- PC3
- SPC3
- Nec-1
- Nec1
- Phpp-1
- BDP
- PC1/3
- proprotein convertase subtilisin/kexin type 1
- prohormone convertase 1
- PCSK1
- Pcsk1
- pcsk1
- PC1B
- Epitop
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Middle Region
Alternativen - Reaktivität
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Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
Alternativen - Wirt
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Kaninchen
Alternativen - Klonalität
- Applikation
-
Immunohistochemistry (IHC), Western Blotting (WB)
Alternativen - Optionen
- Hersteller
- Anmelden zum Anzeigen
- Hersteller Produkt- Nr.
- Anmelden zum Anzeigen
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Bilder
Produktnummer ABIN2778153
$ 289.00
Zzgl. Versandkosten $45.00
Zzgl. Versandkosten $45.00
| Relevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN959007 | IHC (p) WB | Rabbit | AA 683-732 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN2626610 | IHC (p) WB | Rabbit | IgG | AA 726-740 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) Antikörper |
| Epitop | Middle Region Alternativen |
| Reaktivität | Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus) Alternativen |
| Wirt | Kaninchen Alternativen |
| Klonalität | |
| Applikation |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternativen
|
|
1 Publikation vorhanden |
| Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-PCSK1 AntikörperTarget Details PCSK1 Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder |
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| Blocking Peptide | Zu diesem Produkt passt das Blocking Peptide ABIN981479. |
| Sequenz | QSPKKSPSAK LNIPYENFYE ALEKLNKPSQ LKDSEDSLYN DYVDVFYNTK |
| Homologie | Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93% |
| Produktmerkmale | This is a rabbit polyclonal antibody against PCSK1. It was validated on Western Blot using a cell lysate as a positive control. |
| Reinigung | Affinity Purified |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PCSK1 |
Target Details PCSK1Produktdetails anti-PCSK1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben |
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| Antigen | |
| Andere Bezeichnung | PCSK1 (PCSK1 Antibody Abstract) |
| Hintergrund |
PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: NEC1, PC1, PC3, SPC3, BMIQ12 Protein Interaction Partner: env, AFF1, PCSK1N, REN, PMCH, IAPP, PTK2, CTNNB1, Protein Size: 753 |
| Molekulargewicht | 71 kDa |
| Gen-ID | 5122 |
| NCBI Accession | NM_000439, NP_000430 |
| UniProt | P29120 |
| Pathways | Peptide Hormone Metabolism |
AnwendungsinformationenProduktdetails anti-PCSK1 Antikörper Target Details PCSK1 Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben |
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| Applikationshinweise | Optimal working dilutions should be determined experimentally by the investigator. |
| Kommentare |
Antigen size: 753 AA |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben |
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| Format | Liquid |
| Konzentration | Lot specific |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
| Konservierungsmittel | Sodium azide |
| Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handhabung | Avoid repeated freeze-thaw cycles. |
| Lagerung | -20 °C |
| Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Referenzen für anti-PCSK1 Antikörper (ABIN2778153)Produktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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| Allgemeine Veröffentlichungen |
Rehfeld, Bundgaard, Hannibal, Zhu, Norrbom, Steiner, Friis-Hansen: "The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6." in: Endocrinology, Vol. 149, Issue 4, pp. 1600-8, 2008 |
BilderProduktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) zurück nach oben |
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| Bilder des Herstellers |
Immunohistochemistry with Pancreas tissue at an antibody concentration of 5µg/ml usin...
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