anti-Human CHEK1 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended CHEK1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Checkpoint Kinase 1 (CHEK1) Antikörper
  • An08g10320
  • AO090003000441
  • CHK1
  • chk1
  • C85740
  • Chk1
  • rad27
  • id:ibd2720
  • zgc:56093
  • CHEK1
  • checkpoint kinase 1
  • serine/threonine-protein kinase chk1
  • serine/threonine-protein kinase Chk1
  • CAMK/CAMKL/CHK1 protein kinase Chk1
  • checkpoint kinase 1 S homeolog
  • CHEK1
  • ANI_1_2436074
  • AOR_1_768154
  • PTRG_04183
  • SJAG_01680
  • PAAG_04978
  • MCYG_03290
  • VDBG_03742
  • chek1.S
  • Chek1
  • chek1
Epitop
AA 250-300
70
58
40
35
29
16
15
15
15
13
7
6
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
502
205
178
14
14
10
10
10
7
5
4
4
4
2
1
1
Wirt
Kaninchen
441
54
22
6
Klonalität
Polyklonal
Konjugat
Dieser CHEK1 Antikörper ist unkonjugiert
14
13
12
8
8
8
3
3
3
3
3
3
3
3
3
3
3
2
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Proximity Ligation Assay (PLA), Western Blotting (WB)
441
212
176
78
71
40
23
22
18
16
7
7
6
5
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN151911
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13.042537 ABIN4297951 IHC IHC (p) WB Rabbit pSer317 Anmelden zum Anzeigen Polyclonal 3
13.042537 ABIN151295 ICC IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 2G1D5 0
13.042537 ABIN407619 ICC IF IHC (p) IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN214737 IHC IHC (p) WB Rabbit AA 192-241 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN214042 IHC IHC (p) WB Rabbit IgG Ser280 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN447119 IHC (p) IHC Rabbit pSer345 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN4297946 IHC IHC (p) WB Rabbit pSer345 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN498255 IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN498827 IHC (p) Rabbit pSer345 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN498828 IHC (p) Rabbit pSer317 Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN498915 IHC (p) Rabbit Anmelden zum Anzeigen Polyclonal 0
13.042537 ABIN498916 IHC (p) Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN358109 EIA IHC (p) WB Rabbit Ig Fraction pSer317 Anmelden zum Anzeigen Polyclonal 5
1 ABIN358108 EIA IHC (p) WB Rabbit Ig Fraction pSer280 Anmelden zum Anzeigen Polyclonal 5
1 ABIN389542 IHC (p) WB Rabbit Ig Fraction pSer280 Anmelden zum Anzeigen Polyclonal 3
1 ABIN389543 DB IHC (p) WB Rabbit Ig Fraction pSer317 Anmelden zum Anzeigen Polyclonal 3
1 ABIN2857048 ICC IF IHC (p) WB Rabbit IgG Internal Region, pSer345 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2857050 ICC IF IHC (p) WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN439073 ICC IF IHC (p) IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 2
1 ABIN487487 IHC (p) IP WB Mouse IgG2b Anmelden zum Anzeigen DCS-310 0

General

Antigen Checkpoint Kinase 1 (CHEK1) Antikörper
Epitop AA 250-300
(70), (58), (40), (35), (29), (16), (15), (15), (15), (13), (7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(502), (205), (178), (14), (14), (10), (10), (10), (7), (5), (4), (4), (4), (2), (1), (1)
Wirt Kaninchen
(441), (54), (22), (6)
Klonalität
Polyklonal
Konjugat Dieser CHEK1 Antikörper ist unkonjugiert
(14), (13), (12), (8), (8), (8), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Proximity Ligation Assay (PLA), Western Blotting (WB)
(441), (212), (176), (78), (71), (40), (23), (22), (18), (16), (7), (7), (6), (5)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CHEK1 Antikörper

Target Details CHEK1 Anwendungsinformationen Handhabung Referenzen für anti-CHEK1 Antikörper (ABIN151911) Bilder
Reinigung Immunogen affinity purified
Immunogen The immunogen recognized by this antibody maps to a region between residues 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).
Isotyp IgG
Plasmids, Primers & others

Target Details CHEK1

Produktdetails anti-CHEK1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CHEK1 Antikörper (ABIN151911) Bilder zurück nach oben
Antigen
Andere Bezeichnung Chk1 (CHEK1 Antibody Abstract)
Hintergrund Gene Symbol: CHEK1
Molekulargewicht Theoretical MW: 54 kDa
Gen-ID 1111
UniProt O14757
Pathways p53 Signalweg, Apoptose, Zellzyklus

Anwendungsinformationen

Produktdetails anti-CHEK1 Antikörper Target Details CHEK1 Handhabung Referenzen für anti-CHEK1 Antikörper (ABIN151911) Bilder zurück nach oben
Applikations-hinweise Western Blot 1:10000-1:25000, Immunohistochemistry 1:1000-1:5000, Immunocytochemistry/Immunofluorescence 1:500-1:2000, Immunohistochemistry-Paraffin 1:1000-1:5000, Proximity Ligation Assay 1:1000-1:10000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CHEK1 Antikörper Target Details CHEK1 Anwendungsinformationen Referenzen für anti-CHEK1 Antikörper (ABIN151911) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C. Do not freeze.

Referenzen für anti-CHEK1 Antikörper (ABIN151911)

Produktdetails anti-CHEK1 Antikörper Target Details CHEK1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Jazaeri, Shibata, Park, Bryant, Conaway, Modesitt, Smith, Milhollen, Berger, Dutta: "Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924." in: Molecular cancer therapeutics, Vol. 12, Issue 10, pp. 1958-67, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Terai, Shibata, Abbas, Dutta: "Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage." in: The Journal of biological chemistry, Vol. 288, Issue 42, pp. 30509-14, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Hong, Hu, Yuan, Sang, Bu, Chen, Yang, Li, Huang, Chen, Liang, Zhang, Pan, Zeng, Kang: "CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma." in: The Journal of clinical investigation, Vol. 122, Issue 6, pp. 2165-75, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunohistochemistry

Karnani, Dutta: "The effect of the intra-S-phase checkpoint on origins of replication in human cells." in: Genes & development, Vol. 25, Issue 6, pp. 621-33, 2011

Shiotani, Kobayashi, Watanabe, Yamamoto, Sugimura, Wakabayashi: "Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1." in: Molecular cancer research : MCR, Vol. 4, Issue 2, pp. 125-33, 2006

Bai, Wang, Huo, Xie, Xie, Xu, Wang: "Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma." in: Translational oncology, Vol. 11, Issue 1, pp. 140-146, 1970 (Probematerial (Species): Mouse (Murine)).

Bilder

Produktdetails anti-CHEK1 Antikörper Target Details CHEK1 Anwendungsinformationen Handhabung Referenzen für anti-CHEK1 Antikörper (ABIN151911) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Detection of Chk1 in HeLa whole cell lysates using ABIN151911.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Immunohistochemistry-Paraffin: Chk1 Antibody [ABIN151911] - Human testicular seminoma...
Western Blotting (WB) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Western Blot: Chk1 Antibody [ABIN151911] - Whole cell lysate (20 ug) from HeLa cells....
Proximity Ligation Assay (PLA) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Proximity Ligation Assay: Chk1 Antibody [ABIN151911] - Secondary-conjugate Duolink II...
Proximity Ligation Assay (PLA) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Proximity Ligation Assay: Chk1 Antibody [ABIN151911] - Secondary-conjugate Duolink In...
Proximity Ligation Assay (PLA) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Proximity Ligation Assay: Chk1 Antibody [ABIN151911] - Secondary-conjugate Duolink In...
Proximity Ligation Assay (PLA) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Proximity Ligation Assay: Chk1 Antibody [ABIN151911] - Secondary-conjugate Duolink II...
Proximity Ligation Assay (PLA) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Proximity Ligation Assay: Chk1 Antibody [ABIN151911] - Secondary-conjugate Duolink in...
Immunofluorescence (IF) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Immunocytochemistry/Immunofluorescence: Chk1 Antibody [ABIN151911] - NBF-fixed HeLa c...
Immunocytochemistry (ICC) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Immunohistochemistry: Chk1 Antibody - Sample: FFPE section of human breast carcinoma...
Western Blotting (WB) image for anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody (ABIN151911) Western Blot: Chk1 Antibody - Detection of Human Chk1 by Western Blot. Samples: Whol...