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CHEK1 Antikörper (pSer28)

Name: CHEK1 Antikörper (pSer28)
SKU: ABIN537590
Price: 668.25 EUR
Availability: InStock

CHEK1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated

The CHEK1 (phospho S280) polyclonal antibody is used in Western blot to detect Phospho-CHK1-S280 in, from left to right, A2058, Ramos, Jurkat, HL-60, and Hela cell lysates.

The CHEK1 (phospho S280) polyclonal antibody is used in Western blot to detect Phospho-CHK1-S280 in mouse brain tissue lysate.

Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with CHEK1 (phospho S280) polyclonal antibody which was peroxidase-conjugated to the secondary antibody followed by AEC staining.

IHC

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN537590

Datenblatt (PDF)

Target Alle CHEK1 Antikörper anzeigen

CHEK1 (Checkpoint Kinase 1 (CHEK1))
Bindungsspezifität
44

29

26

19

14

13

7

6

5

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer28
Reaktivität
213

118

68

16

9

9

6

5

5

3

3

2

2

1

1
Human, Maus
Wirt
222

14

7

5
Kaninchen
Passende Sekundärantikörper
Klonalität
209

40
Polyklonal
Konjugat
133

13

11

9

9

9

9

8

8

8

5

5

4

4

4

4

4

2
Dieser CHEK1 Antikörper ist unkonjugiert
Applikation
171

87

53

41

40

36

35

17

16

13

10

7

6

3

3

1

1
Western Blotting (WB)

Verwendungszweck

Rabbit polyclonal antibody raised against synthetic phosphopeptide of CHEK1.

Kreuzreaktivität

Human, Maus

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S280 of human CHEK1.

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anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7845-RB18425 unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
CHEK1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In PBS (0.09 % sodium azide).

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Ng, Lee, Ho, Arooz, Siu, Lau, Poon: "Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains." in: The Journal of biological chemistry, Vol. 279, Issue 10, pp. 8808-19, (2004) (PubMed).

Xu, Lee, Stern: "Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34091-4, (2004) (PubMed).

Krämer, Mailand, Lukas, Syljuåsen, Wilkinson, Nigg, Bartek, Lukas: "Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase." in: Nature cell biology, Vol. 6, Issue 9, pp. 884-91, (2004) (PubMed).
Target

CHEK1 (Checkpoint Kinase 1 (CHEK1))

Andere Bezeichnung

CHK1 (CHEK1 Produkte)

Synonyme

An08g10320 antikoerper, AO090003000441 antikoerper, CHK1 antikoerper, chk1 antikoerper, C85740 antikoerper, Chk1 antikoerper, rad27 antikoerper, id:ibd2720 antikoerper, zgc:56093 antikoerper, CHEK1 antikoerper, checkpoint kinase 1 antikoerper, serine/threonine-protein kinase chk1 antikoerper, serine/threonine-protein kinase Chk1 antikoerper, CAMK/CAMKL/CHK1 protein kinase Chk1 antikoerper, checkpoint kinase 1 S homeolog antikoerper, CHEK1 antikoerper, ANI_1_2436074 antikoerper, AOR_1_768154 antikoerper, PTRG_04183 antikoerper, SJAG_01680 antikoerper, PAAG_04978 antikoerper, MCYG_03290 antikoerper, VDBG_03742 antikoerper, chek1.S antikoerper, Chek1 antikoerper, chek1 antikoerper

Gen-ID

1111

Pathways

p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur