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Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Produkte

(Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009].

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Ausgewählte Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Kategorien

Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Antikörper

High quality antibodies with extensive validation data.

Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (5)
Kat. Nr. ABIN184751
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN518586
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN7269401
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969386
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1148326
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1148327
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313891
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313893
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3134596
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Produkten

Kong, Wong, Chan, Lo: "Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex." in: Journal of proteome research, Vol. 12, Issue 11, pp. 5233-45, (2013) (PubMed).

Lo, Chen, Cheng, Hsu, Wang: "Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 3, pp. 585-92, (2012) (PubMed).

Alkuraya, Cai, Emery, Mochida, Al-Dosari, Felie, Hill, Barry, Partlow, Gascon, Kentab, Jan, Shaheen, Feng, Walsh: "Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]." in: American journal of human genetics, Vol. 88, Issue 5, pp. 536-47, (2011) (PubMed).

Lam, Vergnolle, Thorpe, Woodman, Allan: "Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning." in: Journal of cell science, Vol. 123, Issue Pt 2, pp. 202-12, (2010) (PubMed).

Taya, Shinoda, Tsuboi, Asaki, Nagai, Hikita, Kuroda, Kuroda, Shimizu, Hirotsune, Iwamatsu, Kaibuchi: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).

McManus, Golden: "Neuronal migration in developmental disorders." in: Journal of child neurology, Vol. 20, Issue 4, pp. 280-6, (2005) (PubMed).

Green, Wollman, Kaplan: "APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment." in: Molecular biology of the cell, Vol. 16, Issue 10, pp. 4609-22, (2005) (PubMed).

Reiner, Bar-Am, Sapir, Shmueli, Carrozzo, Lindsay, Baldini, Ledbetter, Cahana: "LIS2, gene and pseudogene, homologous to LIS1 (lissencephaly 1), located on the short and long arms of chromosome 2." in: Genomics, Vol. 30, Issue 2, pp. 251-6, (1996) (PubMed).

Hattori, Adachi, Tsujimoto, Arai, Inoue: "Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]." in: Nature, Vol. 370, Issue 6486, pp. 216-8, (1994) (PubMed).

Reiner, Carrozzo, Shen, Wehnert, Faustinella, Dobyns, Caskey, Ledbetter: "Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats." in: Nature, Vol. 364, Issue 6439, pp. 717-21, (1993) (PubMed).

Synonyme und alternative Namen zu Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)

platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1), platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Pafah1b1), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (Pafah1b1), platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog (pafah1b1.L), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a (pafah1b1a), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b (pafah1b1b), platelet activating factor acetylhydrolase 1b regulatory subunit 1 (Pafah1b1), LIS-1, LIS1, Lis1, Lis1a, LIS2, lis2, MDCR, mdcr, MDS, mds, Mdsh, MMS10-U, Ms10u, PAFAH, pafah, pafah1b1-b, Pafaha, PAFAHA

Bezeichner auf Proteinebene für Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)

  • LIS-1
  • PAF acetylhydrolase 45 kDa subunit
  • PAF-AH 45 kDa subunit
  • PAF-AH alpha
  • PAFAH alpha
  • lissencephaly 1 protein
  • lissencephaly-1 protein
  • platelet-activating factor acetylhydrolase IB subunit alpha
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
  • platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
  • platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
  • platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
  • PAF-AH beta
  • platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)
  • platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
  • LIS1
  • lissencephaly-1 homolog
  • lissencephaly-1 homolog B
  • chLIS1
  • platelet-activating factor acetylhydrolase Ib-alpha subunit
  • Miller-Dieker syndrome chromosome region
  • Lissencephaly-1 protein
  • platelet-activating factor acetylhydrolase isoform Ib alpha subunit
  • lis1b
  • lissencephaly-1 homolog A
  • platelet-activating factor acetylhydrolase IB subunit alpha a
  • platelet-activating factor acetylhydrolase IB subunit alpha b
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