anti-Maus NR4A2 Antikörper für Immunofluorescence

Recommended NR4A2 Antibody

Antigen
Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Antikörper
  • nr41/42/43
  • Nr4a2
  • nurr1
  • not
  • rnr1
  • hzf-3
  • tinur
  • NGFI-B
  • HZF-3
  • NOT
  • NURR1
  • RNR1
  • TINUR
  • Nurr1
  • RNR-1
  • TINOR
  • ngf1b
  • nr4a2
  • zgc:92696
  • nuclear receptor subfamily 4 group A member 2
  • nuclear receptor
  • nuclear receptor subfamily 4, group A, member 2
  • nuclear receptor subfamily 4, group A, member 2b
  • NR4A2
  • nr41/42/43
  • nr4a2
  • Nr4a2
  • nr4a2b
Epitop
AA 13-42
9
9
7
6
3
3
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
79
22
19
6
6
5
5
5
5
3
2
2
2
2
2
1
1
Wirt
Kaninchen
59
22
Klonalität
Polyklonal
Konjugat
Dieser NR4A2 Antikörper ist unkonjugiert
5
3
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
63
38
23
10
6
4
3
2
1
1
Optionen

Bilder

Produktnummer ABIN3032065
$ 452.38
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
10 ABIN5537220 IF IHC (p) WB Rabbit Ig Fraction AA 13-42, N-Term Polyclonal 0
1 ABIN2626315 ICC IF WB Rabbit IgG AA 344-530 Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Antikörper
Epitop AA 13-42
(9), (9), (7), (6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(79), (22), (19), (6), (6), (5), (5), (5), (5), (3), (2), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(59), (22)
Klonalität
Polyklonal
Konjugat Dieser NR4A2 Antikörper ist unkonjugiert
(5), (3), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(63), (38), (23), (10), (6), (4), (3), (2), (1), (1)
Hersteller

Produktdetails anti-NR4A2 Antikörper

Target Details NR4A2 Anwendungsinformationen Handhabung Bilder
Kreuzreaktivität (Details) Expected species reactivity: Rat, Bovine
Reinigung Purified
Immunogen A portion of amino acids 13-42 from the human protein was used as the immunogen for this NURR1 antibody.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details NR4A2

Produktdetails anti-NR4A2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung NURR1 (NR4A2 Antibody Abstract)
Hintergrund Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is critical for the development of dopamine (DA) neurons. It belongs to the conserved family of nuclear receptors but lacks an identified ligand and is therefore referred to as an orphan receptor. RXR ligands can promote the survival of DA neurons via a process that depends on Nurr1-RXR heterodimers. In developing DA cells, Nurr1 is required for the expression of several genes important for DA synthesis and function. Nurr1 is also important for the maintenance of adult DA neurons.
UniProt P43354
Pathways Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway

Anwendungsinformationen

Produktdetails anti-NR4A2 Antikörper Target Details NR4A2 Handhabung Bilder zurück nach oben
Applikations-hinweise Titration of the NURR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-NR4A2 Antikörper Target Details NR4A2 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Aliquot the NURR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Bilder

Produktdetails anti-NR4A2 Antikörper Target Details NR4A2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody (ABIN3032065) Confocal immunofluorescent analysis of NURR1 antibody with HeLa cells followed by Ale...
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody (ABIN3032065) IHC analysis of FFPE human brain tissue stained with NURR1 antibody
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody (ABIN3032065) NR4A2 antibody western blot analysis in HeLa lysate
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody (ABIN3032065) NR4A2 antibody western blot analysis in HeLa lysate
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody (ABIN3032065) Confocal immunofluorescent analysis of NURR1 antibody with HeLa cells followed by Ale...