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anti-Mouse (Murine) IL1B Antikörper:
anti-Rat (Rattus) IL1B Antikörper:
anti-Human IL1B Antikörper:
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Bacteria Polyclonal IL1B Primary Antibody für ELISA, EM - ABIN269770
Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. in Autophagy 2011
Show all 16 Pubmed References
Human Monoclonal IL1B Primary Antibody für CyTOF, FACS - ABIN4899223
Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000
Show all 15 Pubmed References
Dog (Canine) Polyclonal IL1B Primary Antibody für IF (p), IHC (p) - ABIN728503
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011
Show all 11 Pubmed References
Human Polyclonal IL1B Primary Antibody für ELISA, ICC - ABIN6262623
Ding, Xu, Wang, Zhang: Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation. in Medical science monitor : international medical journal of experimental and clinical research 2016
Show all 9 Pubmed References
Human Polyclonal IL1B Primary Antibody für IHC (p), IHC - ABIN446969
Omran, Peng, Zhang, Xiang, Xue, Gan, Kong, Yin: Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. in Epilepsia 2012
Show all 7 Pubmed References
Mouse (Murine) Polyclonal IL1B Primary Antibody für Neut, WB - ABIN223538
Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 6 Pubmed References
Mouse (Murine) Monoclonal IL1B Primary Antibody für IP, Neut - ABIN1176987
Fei, Gott, Edwards, Schuyler: Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. in The Journal of laboratory and clinical medicine 1995
Show all 4 Pubmed References
Human Polyclonal IL1B Primary Antibody für FACS, IHC (p) - ABIN652470
Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996
Show all 5 Pubmed References
Mouse (Murine) Polyclonal IL1B Primary Antibody für ELISA, FACS - ABIN4324365
Triantafilou, Kar, Vakakis, Kotecha, Triantafilou: Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. in Thorax 2012
Show all 4 Pubmed References
Human Monoclonal IL1B Primary Antibody für FACS - ABIN4895764
Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002
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This study reveals that proper levels of Il1b signaling and tissue inflammation, which are tuned by macrophages, play a crucial role in tissue regeneration.
Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (zeige CASP3 Antikörper) dependent manner.
Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.
findings reveal that the Il-1beta-Myd88 (zeige MYD88 Antikörper) axis and NADPH oxidase (zeige NOX1 Antikörper)-mediated ROS (zeige ROS1 Antikörper) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.
the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae
These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.
In fibrocystin/polyductin (zeige PKHD1 Antikörper) complex-defective cholangiocytes, beta-catenin (zeige CTNNB1 Antikörper) and IL-1beta are responsible for signal transducer and activator of transcription 3 (zeige STAT3 Antikörper)-dependent secretion of CXCL10 (zeige CXCL10 Antikörper)
These results suggest that mitochondrial ROS (zeige ROS1 Antikörper)-TXNIP (zeige TXNIP Antikörper)/NLRP3 (zeige NLRP3 Antikörper)/IL-1beta axis activation is responsible for tubular oxidative injury, which can be ameliorated by MitoQ via the inhibition of mtROS overproduction
Circadian clock protein BMAL1 (zeige ARNTL Antikörper) regulates IL-1beta in macrophages via NRF2 (zeige NFE2L2 Antikörper).
TLR2 and NLRP3 (zeige NLRP3 Antikörper) inflammasome activation in cardiac macrophages mediate the production of IL-1beta in diabetic mice. IL-1beta causes prolongation of the action potential duration, induces a decrease in potassium current and an increase in calcium sparks in cardiomyocytes, which are changes that underlie arrhythmia propensity.
show that mutant KRAS facilitates IKKalpha (zeige CHUK Antikörper)-mediated responsiveness of tumor cells to host IL-1beta, thereby establishing a host-to-tumor signaling circuit that culminates in inflammatory MPE development and drug resistance
identify interleukin-1 beta as an upstream trigger for the upregulation of interactions between USP5 (zeige USP5 Antikörper) and Cav3.2 (zeige CACNA1H Antikörper) channels in the pain pathway
The present study demonstrated that IL-1b may induce ICAM-1 (zeige ICAM1 Antikörper) expression, thus enhancing the cohesion between mesenchymal stem cells and endothelial progenitor cells via the p38 MAPK (zeige MAPK14 Antikörper) signaling pathway.
SAG2A differentially modulates IL-1beta expression in resistant and susceptible murine peritoneal macrophages cells.
High IL-1beta expression is associated with experimental autoimmune encephalomyelitis.
tibias of botulin A toxin-treated and tail-suspended mice, which featured unloading and decreased bone mass, showed higher expression of IL-1beta, Lcn2 and Nos2, suggesting their pathophysiologic involvement in endothelial cell-osteoblast crosstalk.
Taken together, the silencing of H4R (zeige HRH4 Antikörper) inhibited the H4R (zeige HRH4 Antikörper) mediated Mast cell functions and SAPK (zeige MAPK9 Antikörper)/JNK (zeige MAPK8 Antikörper) phosphorylation. Furthermore, the H4R (zeige HRH4 Antikörper) activation utilized SAPK (zeige MAPK9 Antikörper)/JNK (zeige MAPK8 Antikörper) signaling pathway for IL-1beta release in HMC-1 cells
IL-1beta/IL-6 (zeige IL6 Antikörper) network is highly expressed in the colorectal cancer (CRC (zeige CALR Antikörper)) microenvironment, indicating that this network is important in the progression of CRC (zeige CALR Antikörper)
Findings revealed an HIF-1alpha (zeige HIF1A Antikörper)/IL-1beta signaling loop between cancer cells and tumor-associated macrophages in a hypoxic microenvironment, resulting in cancer cell epithelial-mesenchymal transition and metastasis; more importantly, our results suggest a potential role of an anti-inflammatory strategy in hepatocellular carcinoma treatment
Colombian individuals with high African ancestry proportions at locus 2q14 harbour more IL1B-CGTC copies and are consequently at an increased risk of colorectal cancer.
Study found a statistically significant association between the IL-1B rs16944 polymorphism and febrile seizures (FS) risk in Caucasians and Asians. The TT+CT genotypes were associated with a 1.43 times increased risk for FS in Caucasians, while an increased risk of 1.39 times was observed for FS development for the TT homozygotes in Asians.
Preincubation of LAD2 cells with the natural flavonoid methoxyluteolin (1-100 mM) inhibits (P < 0.0001) secretion and gene expression of IL-1beta, procaspase-1, and pro-IL-1beta. Mast cell secretion of IL-1beta in response to SP and IL-33 (zeige IL33 Antikörper) reveals targets for the development of antiinflammatory therapies.
in Caco-2 CFTR (zeige CFTR Antikörper)-shRNA cells, the EGFR (zeige EGFR Antikörper) ligand EREG (zeige EREG Antikörper) is overexpressed due to an active IL-1beta autocrine loop that indirectly activates EGFR (zeige EGFR Antikörper), constituting new signaling effectors for the CFTR (zeige CFTR Antikörper) signaling pathway, downstream of CFTR (zeige CFTR Antikörper), Cl(-) , and IL-1beta.
The single nucleotide polymorphism (SNP) of IL-1beta gene (rs3917356G>A) increased the risk of HCC (zeige FAM126A Antikörper) in the recessive model (p<0.001, OR=2.58, 95% CI=1.53-4.33), whereas other SNPs in IL-1alpha and IL-1RA (zeige IL1RN Antikörper) showed no significant association between Hepatocellular carcinoma patients and controls.
Caspase-1 (zeige CASP1 Antikörper)-dependent IL-1beta processing and secretion require the AIM2 (zeige AIM2 Antikörper) inflammasome pathway in human dental pulp cells and the AIM2 (zeige AIM2 Antikörper) inflammasome pathway is critical for regulation of the dental pulp immune response.
Genetic Polymorphisms of IL1B, IL6, and TNFalpha in a Chinese Han Population with Pulmonary Tuberculosis.
Analysis of host-protein interactions for African swine fever virus L83L identified IL-1beta as its host ligand. A recombinant African swine fever virus lacking the L83L was developed from the highly virulent field isolate Georgia2007 and was used to show that L83L is a non-essential gene.
This study showed that the presence of embryos in oviducts on days 2-3 after mating may influence the oviductal expression of the members of the IL-1beta system, determining the action of IL-1beta, which may be considered to be the earliest sign of pregnancy in pigs.
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
local expression of IL-1beta and IL-8 (zeige IL8 Antikörper) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
IL1B regulates expression of IL1R1 (zeige IL1RN Antikörper) and IL1RAP (zeige IL1RAP Antikörper) and stimulates expression of PTGS1 (zeige PTGS1 Antikörper) and PTGS2 (zeige PTGS2 Antikörper) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (zeige PLIN1 Antikörper)-implantation period of pregnancy in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
Mycobacterium bovis infected animals have a higher frequency of IFN-gamma (zeige IFNG Antikörper) producing CD4 (zeige CD4 Antikörper)(+) T cells and elevated plasma IL-1beta levels.
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (zeige IL1RN Antikörper) protein and IL1B and IL1R1 (zeige IL1RN Antikörper) mRNA were detected.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (zeige P2RX7 Antikörper).
Role of TGF-beta1 (zeige TGFB1 Antikörper) and TNF-alpha (zeige TNF Antikörper) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Testicular IL-1 alpha (zeige IL1A Antikörper) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (zeige IL1A Antikörper) bioactivity and IL-6 (zeige IL6 Antikörper) concentrations were greatest in the immediate pre-pubertal period.
Data describe the expression of IL-8 (zeige IL8 Antikörper), IL-1beta and their respective receptors, CXCR1 (zeige CXCR1 Antikörper) and IL-1R1 in bovine theca cells, and suggest that VEGF (zeige VEGFA Antikörper) is associated with the IL system in theca cells in ovary.
Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (zeige PGF Antikörper)(2alpha) and PGE (zeige LIPF Antikörper)(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1 (zeige IL1A Antikörper)-induced matrix degradation and loss of tissue material properties
dynamic compression stimulates cell proliferation and proteoglycan (zeige Vcan Antikörper) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (zeige JUN Antikörper) signalling pathways
These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (zeige TNF Antikörper) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (zeige IL6 Antikörper) in rabbit cornea cells.
IL-1beta and TNF-alpha (zeige TNF Antikörper) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (zeige TNF Antikörper).
IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (zeige SLC2A5 Antikörper) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.
The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.
Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (zeige TGFB1 Antikörper), which delays the development of osteoarthritis.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (zeige COX2 Antikörper), and TGFbeta1 (zeige TGFB1 Antikörper)
Increased PGE2 production led to reduction in 5-LO (zeige ALOX5 Antikörper) products in LPS (zeige IRF6 Antikörper)-treated equine whole blood via IL-1b.
Results suggested that chemokine (zeige CCL1 Antikörper) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
IL-1beta-induced up-regulation of matrix metalloproteinase 13 (zeige MMP13 Antikörper) mRNA was blocked by all concentrations of geldanamycin tested
This study examined effects of in vitro exposure to solutions of hay (zeige GTF2H5 Antikörper) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
, IL-1 beta
, interleukin-1 beta
, preinterleukin 1 beta
, prointerleukin-1 beta
, Interleukin-1 beta
, precursor interleukin-1beta
, interleukin-1 beta proprotein
, interleukin 1 beta
, lymphocyte proliferation-potentiating factor