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anti-Mouse (Murine) IL1B Antikörper:
anti-Rat (Rattus) IL1B Antikörper:
anti-Human IL1B Antikörper:
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Human Monoclonal IL1B Primary Antibody für CyTOF, FACS - ABIN4899224
Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000
Show all 15 Pubmed References
Human Monoclonal IL1B Primary Antibody für CyTOF, FACS - ABIN4899223
Oliver, Lovric, Yu, Christou, Aiken, Cooper, Walsh: Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue. in PLoS ONE 2015
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Bacteria Polyclonal IL1B Primary Antibody für ELISA, EM - ABIN269770
Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. in Autophagy 2011
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Dog (Canine) Polyclonal IL1B Primary Antibody für IF (p), IHC (p) - ABIN728503
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011
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Dog (Canine) Polyclonal IL1B Primary Antibody für IHC, ELISA - ABIN1582289
Choi, Lim, Hwang, Lee, Cho, Kim: Anti-ischemic and anti-inflammatory activity of (S)-cis-verbenol. in Free radical research 2010
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Mouse (Murine) Polyclonal IL1B Primary Antibody für Neut, WB - ABIN223538
Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Polyclonal IL1B Primary Antibody für IHC (p), IHC - ABIN446969
Omran, Peng, Zhang, Xiang, Xue, Gan, Kong, Yin: Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. in Epilepsia 2012
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Mouse (Murine) Monoclonal IL1B Primary Antibody für IP, Neut - ABIN1176987
Fei, Gott, Edwards, Schuyler: Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. in The Journal of laboratory and clinical medicine 1995
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Mouse (Murine) Polyclonal IL1B Primary Antibody für ELISA, FACS - ABIN4324365
Triantafilou, Kar, Vakakis, Kotecha, Triantafilou: Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. in Thorax 2012
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Human Monoclonal IL1B Primary Antibody für FACS - ABIN4895764
Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002
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This study reveals that proper levels of Il1b signaling and tissue inflammation, which are tuned by macrophages, play a crucial role in tissue regeneration.
Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (zeige CASP3 Antikörper) dependent manner.
Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.
findings reveal that the Il-1beta-Myd88 (zeige MYD88 Antikörper) axis and NADPH oxidase (zeige NOX1 Antikörper)-mediated ROS (zeige ROS1 Antikörper) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.
the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae
These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.
Alendronate (ALN (zeige TTC21B Antikörper))-augmented IL-1beta production and cell death require Smad3 (zeige SMAD3 Antikörper) and ASC (zeige STS Antikörper) activation, and SIS3 and anti-ASC (zeige STS Antikörper) antibodies may serve as palliative agents for necrotizing inflammatory diseases caused by ALN (zeige TTC21B Antikörper)
urinary LRG (zeige LRG1 Antikörper) is produced in renal tubular epithelial cells by interleukin-1beta (IL-1beta) that is released during proteinuria-induced renal damage
These data reveal how, upon XIAP (zeige XIAP Antikörper) deficiency, a TLR-TNF (zeige TNF Antikörper)-TNFR2 (zeige TNFRSF1B Antikörper) axis drives cIAP1 (zeige BIRC2 Antikörper)-TRAF2 (zeige TRAF2 Antikörper) degradation to allow TLR or TNFR1 (zeige TNFRSF1A Antikörper) activation of RIPK3 (zeige RIPK3 Antikörper)-caspase-8 (zeige CASP8 Antikörper) and IL-1beta. This mechanism may explain why XIAP (zeige XIAP Antikörper)-deficient patients can exhibit symptoms reminiscent of patients with activating inflammasome mutations.
IL-1beta exerts variable effects on long-term potentiation at different kinds of synapses, indicating that IL-1beta has synapse-specific effects on hippocampal synaptic plasticity.
we assessed the role of RIP3 (zeige MPRIP Antikörper) in synergy with Caspase-1 (zeige CASP1 Antikörper) in the induction of IL-1beta production in BMDM after either LPS (zeige TLR4 Antikörper)/ATP or Chlamydia muridarum stimulation. The possibility of pyroptosis and necroptosis interplays and the role of RIP3 (zeige MPRIP Antikörper) in IL-1beta production during Chlamydia muridarum infection in BMDM was investigated as well.
Inhibition of signaling stimulated by both TNF (zeige TNF Antikörper) and IL1beta synergizes with NF-kappaB (zeige NFKB1 Antikörper) inhibition in eliminating leukemic stem cells.
Parenchymal polymorphonuclear myeloid-derived suppressor cell (PMN (zeige TBCE Antikörper)-MDSC), have a positive correlation with IL1a (zeige IL1A Antikörper), IL8 (zeige IL8 Antikörper), CXCL5 (zeige CXCL5 Antikörper), and Mip-1a (zeige CCL3 Antikörper), suggesting they may attract PMN (zeige TBCE Antikörper)-MDSC into the tumor
Chemokine receptor 2 (CCR2 (zeige CCR2 Antikörper)(+)) monocytes invade the hippocampus between 1 and 3 d after SE. In contrast, only an occasional CD3 (zeige CD3E Antikörper)(+) T lymphocyte was encountered 3 d after SE. The initial cellular sources of the chemokine (zeige CCL1 Antikörper) CCL2 (zeige CCL2 Antikörper), a ligand for CCR2 (zeige CCR2 Antikörper), included perivascular macrophages and microglia. The induction of the proinflammatory cytokine IL-1beta was greater in FACS-isolated microglia than in brain-invading monocytes
hypernociception in experimental model of autoimmune encephalomyelitis may be a consequence of the increase in some cytokines in dorsal root ganglia, especially IL-1beta.
An OA model was established in mouse articular chondrocytes (MACs) treated by interleukin-1beta (IL-1beta).
This study demonstrated that IL1B expression levels are related to major depressive disorder and conjunctly mediate the effect of childhood maltreatment history on the risk of developing major depressive disorder.
GDNF has a role in lower than expected motor development, but while IL-1beta and CXCL8/IL-8 (zeige IL8 Antikörper) values were higher in the group with typical motor development among preterm neonates
Our findings call into question the role of IL-1beta in the diabetic pancreas as it has been proposed in previous literature. Additionally, our results regarding the localization of IL-1beta should lead to further investigation into the role of IL-1beta in the physiology of pancreatic alpha cells.
IL-1beta rs1143627 polymorphism is not related to periodontal disease susceptibility in the overall population based on the current evidence.
Our results do not show any evidence of association between COPD (zeige ARCN1 Antikörper) and IL-1beta -511 and +3954 gene polymorphisms in Turkish population
Our findings suggest that AhR (zeige AHR Antikörper)-mediated IL-1beta regulation in cerebral endothelium could induce BBB (zeige ALMS1 Antikörper) breakdown and contribute to the pathogenesis of a variety of neurologic disorders.
the IL1B -511 T > C polymorphism may serve as important risk factor for recurrent miscarriage while the IL6 (zeige IL6 Antikörper) -634C > G polymorphism may protect against the risk of recurrent miscarriage
Our data suggests that the polymorphism in genes IL-1beta, IL-1Ra (zeige IL1RN Antikörper) and FABP1 (zeige FABP1 Antikörper) included in this study are not associated with PCOS development, but can influence important biochemical and metabolic parameters in PCOS.
both RAGE (zeige AGER Antikörper) and mitochondrial damage primed NLRP3 (zeige NLRP3 Antikörper) and pro-IL-1beta activation as upstream signals of NF-kappaB (zeige NFKB1 Antikörper) activity, whereas mitochondrial damage was critical for the assembly of inflammasome components. These results revealed that accumulation of AGEs in NP tissue may initiate inflammation-related degeneration of the intervertebral disc via activation of the NLRP3 (zeige NLRP3 Antikörper) inflammasome.
Here, the authors used a set of isogenic streptococcal NAD(+)-glycohydrolase mutants and a macrophage infection model and report that streptococcal streptococcal NAD(+)-glycohydrolase inhibits the innate immune response by decreasing inflammasome-dependent interleukin 1beta (IL-1beta) release from infected macrophages.
This study showed that the presence of embryos in oviducts on days 2-3 after mating may influence the oviductal expression of the members of the IL-1beta system, determining the action of IL-1beta, which may be considered to be the earliest sign of pregnancy in pigs.
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
local expression of IL-1beta and IL-8 (zeige IL8 Antikörper) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
IL1B regulates expression of IL1R1 (zeige IL1RN Antikörper) and IL1RAP (zeige IL1RAP Antikörper) and stimulates expression of PTGS1 (zeige PTGS1 Antikörper) and PTGS2 (zeige PTGS2 Antikörper) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (zeige PLIN1 Antikörper)-implantation period of pregnancy in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
Mycobacterium bovis infected animals have a higher frequency of IFN-gamma (zeige IFNG Antikörper) producing CD4 (zeige CD4 Antikörper)(+) T cells and elevated plasma IL-1beta levels.
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (zeige IL1RN Antikörper) protein and IL1B and IL1R1 (zeige IL1RN Antikörper) mRNA were detected.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (zeige P2RX7 Antikörper).
Role of TGF-beta1 (zeige TGFB1 Antikörper) and TNF-alpha (zeige TNF Antikörper) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Testicular IL-1 alpha (zeige IL1A Antikörper) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (zeige IL1A Antikörper) bioactivity and IL-6 (zeige IL6 Antikörper) concentrations were greatest in the immediate pre-pubertal period.
Data describe the expression of IL-8 (zeige IL8 Antikörper), IL-1beta and their respective receptors, CXCR1 (zeige CXCR1 Antikörper) and IL-1R1 in bovine theca cells, and suggest that VEGF (zeige VEGFA Antikörper) is associated with the IL system in theca cells in ovary.
Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (zeige PGF Antikörper)(2alpha) and PGE (zeige LIPF Antikörper)(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1 (zeige IL1A Antikörper)-induced matrix degradation and loss of tissue material properties
dynamic compression stimulates cell proliferation and proteoglycan (zeige Vcan Antikörper) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (zeige JUN Antikörper) signalling pathways
These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (zeige TNF Antikörper) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (zeige IL6 Antikörper) in rabbit cornea cells.
IL-1beta and TNF-alpha (zeige TNF Antikörper) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (zeige TNF Antikörper).
IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (zeige SLC2A5 Antikörper) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.
The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.
Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (zeige TGFB1 Antikörper), which delays the development of osteoarthritis.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (zeige COX2 Antikörper), and TGFbeta1 (zeige TGFB1 Antikörper)
Increased PGE2 production led to reduction in 5-LO (zeige ALOX5 Antikörper) products in LPS (zeige IRF6 Antikörper)-treated equine whole blood via IL-1b.
Results suggested that chemokine (zeige CCL1 Antikörper) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
IL-1beta-induced up-regulation of matrix metalloproteinase 13 (zeige MMP13 Antikörper) mRNA was blocked by all concentrations of geldanamycin tested
This study examined effects of in vitro exposure to solutions of hay (zeige GTF2H5 Antikörper) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
, IL-1 beta
, interleukin-1 beta
, preinterleukin 1 beta
, prointerleukin-1 beta
, Interleukin-1 beta
, precursor interleukin-1beta
, interleukin-1 beta proprotein
, interleukin 1 beta
, lymphocyte proliferation-potentiating factor