anti-Human BAD Antikörper für Dot Blot

Recommended BAD Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
BCL2-Associated Agonist of Cell Death (BAD) Antikörper
  • bad
  • fa01b12
  • wu:fa01b12
  • wu:fa96d04
  • BAD
  • BBC2
  • BCL2L8
  • AI325008
  • Bbc2
  • BCL2-associated agonist of cell death b
  • BCL2 associated agonist of cell death
  • BCL2-associated agonist of cell death
  • badb
  • BAD
  • Bad
Epitop
pSer99
62
58
48
47
46
46
46
39
33
22
19
19
19
19
19
19
18
18
18
18
18
18
18
18
18
18
18
18
17
17
15
14
14
11
11
11
10
10
9
8
7
7
6
5
5
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
789
474
305
19
19
8
5
4
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
1001
46
2
1
Klonalität
Polyklonal
Konjugat
Dieser BAD Antikörper ist unkonjugiert
67
66
66
61
61
60
6
6
6
6
6
6
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Dot Blot (DB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA
549
547
404
347
132
79
54
36
17
13
11
10
6
3
2
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3030130
$ 452.38
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
20.833187 ABIN2970930 DB IF/ICC IHC Rabbit IgG pSer99 Anmelden zum Anzeigen Polyclonal 0
19.333187 ABIN1539690 DB Rabbit Ig pSer1159 Anmelden zum Anzeigen Polyclonal 1
19.333187 ABIN1539741 DB Rabbit Ig pTyr158 Anmelden zum Anzeigen Polyclonal 1
19.333187 ABIN1881101 DB Rabbit pSer57 Anmelden zum Anzeigen Polyclonal 2
19.333187 ABIN1881099 DB Rabbit pSer32 Anmelden zum Anzeigen Polyclonal 2
19.333187 ABIN1881100 DB Rabbit pThr80 Anmelden zum Anzeigen Polyclonal 2
19.333187 ABIN1881098 DB Rabbit pSer124 Anmelden zum Anzeigen Polyclonal 2
17.833187 ABIN389521 DB IF IHC (p) Rabbit Ig Fraction pSer99 Anmelden zum Anzeigen Polyclonal 2
14.833187 ABIN1539776 DB Rabbit Ig pSer74 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539737 DB Rabbit Ig pTyr110 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539722 DB Rabbit Ig pThr137 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539773 DB Rabbit Ig pSer71 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539706 DB Rabbit Ig AA 41-70, pSer64 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539757 DB Rabbit Ig pSer1041 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539698 DB Rabbit Ig pSer25 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539717 DB Rabbit Ig pSer91 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN1539752 DB Rabbit Ig pTyr76 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN3030133 DB ELISA Rabbit Ig Fraction pTyr110 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN3030131 DB ELISA Rabbit Ig Fraction pThr137 Anmelden zum Anzeigen Polyclonal 0
14.833187 ABIN3030119 DB ELISA Rabbit Ig Fraction pSer124 Anmelden zum Anzeigen Polyclonal 0

General

Antigen BCL2-Associated Agonist of Cell Death (BAD) Antikörper
Epitop pSer99
(62), (58), (48), (47), (46), (46), (46), (39), (33), (22), (19), (19), (19), (19), (19), (19), (18), (18), (18), (18), (18), (18), (18), (18), (18), (18), (18), (18), (17), (17), (15), (14), (14), (11), (11), (11), (10), (10), (9), (8), (7), (7), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(789), (474), (305), (19), (19), (8), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(1001), (46), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser BAD Antikörper ist unkonjugiert
(67), (66), (66), (61), (61), (60), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Applikation Dot Blot (DB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA
(549), (547), (404), (347), (132), (79), (54), (36), (17), (13), (11), (10), (6), (3), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-BAD Antikörper

Target Details BAD Anwendungsinformationen Handhabung Bilder
Kreuzreaktivität (Details) Expected species reactivity: Mouse, Rat
Reinigung Antigen affinity purified
Immunogen This phospho-Bad antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS99 of human Bad.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details BAD

Produktdetails anti-BAD Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Bad (BAD Antibody Abstract)
Hintergrund Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin are found to be involved in the regulation of this protein. Bad is phosphorylated on one or more of Ser-75, Ser-99, Ser-118 and Ser-134 in response to survival stimuli, which blocks its pro-apoptotic activity. Phosphorylation on Ser-99 or Ser-75 promotes heterodimerization with 14-3-3 proteins. This interaction then facilitates the phosphorylation at Ser-118, a site within the BH3 motif, leading to the release of Bcl-X(L) and the promotion of cell survival. Ser-99 is the major site of AKT/PKB phosphorylation, Ser-118 the major site of protein kinase A (CAPK) phosphorylation.
UniProt Q92934
Pathways MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-BAD Antikörper Target Details BAD Handhabung Bilder zurück nach oben
Applikations-hinweise Titration of the phospho-Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Dot blot: 1:500,IHC (Paraffin): 1:50-1:100
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-BAD Antikörper Target Details BAD Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer In 1X PBS,  pH 7.4, with 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Aliquot the phospho-Bad antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Bilder

Produktdetails anti-BAD Antikörper Target Details BAD Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Dot Blot (DB) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibody (ABIN3030130) Dot blot analysis of phospho-Bad antibody. 50ng of phos-peptide or nonphos-peptide pe...
Immunofluorescence (IF) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibody (ABIN3030130) Fluorescent confocal image of HeLa cells stained with phospho-Bad antibody at 1:200. ...
Immunohistochemistry (IHC) image for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibody (ABIN3030130) IHC analysis of FFPE human breast carcinoma tissue stained with the phospho-Bad antib...