anti-Human SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
  • DAP1
  • GMP1
  • OFC10
  • PIC1
  • SENP2
  • SMT3
  • SMT3C
  • SMT3H3
  • UBL1
  • hm:zeh0670
  • wu:fb74c02
  • wu:fd12c02
  • zgc:65934
  • zgc:85634
  • SUMO1
  • dap1
  • gmp1
  • ofc10
  • pic1
  • senp2
  • smt3
  • smt3c
  • sumo-1
  • sumo1
  • ubl1
  • xsumo-1
  • xsumo1
  • ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1
  • ATSUMO1
  • F10M23.180
  • F10M23_180
  • SMALL UBIQUITIN-LIKE MODIFIER 1
  • SUM1
  • SUMO 1
  • small ubiquitin-like modifier 1
  • pigSUMO1
  • SENTRIN
  • SMTP3
  • SUMO-1
  • Smt3C
  • Ubl1
  • small ubiquitin-like modifier 1
  • small ubiquitin-like modifier 1 S homeolog
  • small ubiquitin-related protein 1
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • Sumo1
  • SUMO1
  • sumo1
  • sumo1.S
  • sumo-1
Reaktivität
Human
345
152
109
9
8
7
7
6
5
3
3
2
2
1
1
1
1
1
Wirt
Kaninchen
212
127
4
2
2
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
17
15
14
10
10
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
276
142
138
123
113
110
66
51
40
39
10
9
6
2
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN955007
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.839581 ABIN214521 IHC (p) WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
12.839581 ABIN4914409 IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 66AT1273-94 0
1 ABIN1882136 FACS IF IHC (p) WB Rabbit AA 1-30, N-Term Anmelden zum Anzeigen Polyclonal 9
1 ABIN388027 FACS IHC (p) WB Rabbit Ig Fraction AA 55-86, C-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN356734 EIA IF IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 6
1 ABIN356808 EIA IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 7
1 ABIN1882137 FACS IF IHC (p) WB Rabbit AA 52-79, Glu67, N-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN303292 IHC (p) WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN650618 FACS IF IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 2
1 ABIN657634 IF IHC (p) WB Rabbit Ig Fraction AA 1-30, N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2452138 IF IHC (p) ELISA WB Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
1 ABIN2452136 IF IHC (p) WB FITC Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
1 ABIN2452137 IF IHC (p) ELISA WB Biotin Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
1 ABIN948607 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 1-101, full length Anmelden zum Anzeigen 3D7 0
1 ABIN5552006 EIA IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 0
1 ABIN687397 IF (p) IHC (p) Rabbit IgG AA 20-70 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2879035 IF IHC (p) ELISA WB Rabbit IgG AA 1-50 Anmelden zum Anzeigen Polyclonal 0
1 ABIN271962 IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN5555278 EIA IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1386813 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
Reaktivität Human
(345), (152), (109), (9), (8), (7), (7), (6), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(212), (127), (4), (2), (2), (1), (1)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(17), (15), (14), (10), (10), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Applikation Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(276), (142), (138), (123), (113), (110), (66), (51), (40), (39), (10), (9), (6), (2), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody reacts to SUMO1.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Immunogen Human SUMO1 recombinant protein
Isotyp Ig Fraction

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung SUMO1 (SUMO1 Antibody Abstract)
Hintergrund Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.Synonyms: GAP-modifying protein 1, GMP1, SMT3 homolog 3, SMT3C, SMT3H3, Sentrin, Small ubiquitin-related modifier 1, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
Molekulargewicht 11557 Da
Gen-ID 7341
NCBI Accession NP_001005781
Pathways M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Yang, Sharrocks: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, 2004

Ling, Sankpal, Robertson, McNally, Karpova, Robertson: "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription." in: Nucleic acids research, Vol. 32, Issue 2, pp. 598-610, 2004

Bailey, OHare: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, 2003

Pountney, Huang, Burns, Haan, Thompson, Blumbergs, Gai: "SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease." in: Experimental neurology, Vol. 184, Issue 1, pp. 436-46, 2003

Ohshima, Shimotohno: "Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 50833-42, 2003

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) antibody (ABIN955007) SUMO1 Antibody flow cytometry analysis of MCF-7 cells (bottom histogram) compared to ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) antibody (ABIN955007) Formalin-fixed and paraffin-embedded human brain tissue reacted with SUMO1 Antibody, ...
Western Blotting (WB) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) antibody (ABIN955007) Western blot analysis of SUMO1 Antibody in MCF-7 cell line lysates (35µg/lane). SUMO1...