anti-Human SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antikörper für Immunofluorescence

Recommended SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
  • DAP1
  • GMP1
  • OFC10
  • PIC1
  • SENP2
  • SMT3
  • SMT3C
  • SMT3H3
  • UBL1
  • hm:zeh0670
  • wu:fb74c02
  • wu:fd12c02
  • zgc:65934
  • zgc:85634
  • SUMO1
  • dap1
  • gmp1
  • ofc10
  • pic1
  • senp2
  • smt3
  • smt3c
  • sumo-1
  • sumo1
  • ubl1
  • xsumo-1
  • xsumo1
  • ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1
  • ATSUMO1
  • F10M23.180
  • F10M23_180
  • SMALL UBIQUITIN-LIKE MODIFIER 1
  • SUM1
  • SUMO 1
  • small ubiquitin-like modifier 1
  • pigSUMO1
  • SENTRIN
  • SMTP3
  • SUMO-1
  • Smt3C
  • Ubl1
  • small ubiquitin-like modifier 1
  • small ubiquitin-like modifier 1 S homeolog
  • small ubiquitin-related protein 1
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • Sumo1
  • SUMO1
  • sumo1
  • sumo1.S
  • sumo-1
Epitop
AA 1-30, N-Term
45
15
15
14
14
7
7
6
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
345
152
109
9
8
7
7
6
5
3
3
2
2
1
1
1
1
1
Wirt
Kaninchen
212
127
4
2
2
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
17
15
14
10
10
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
276
142
137
123
113
110
66
51
40
39
10
10
6
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN1882136
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.715723 ABIN2707750 IC IF IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN1533443 IF IHC ELISA WB Rabbit IgG AA 1-50 Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN1882137 FACS IF IHC (p) WB Rabbit AA 52-79, Glu67, N-Term Anmelden zum Anzeigen Polyclonal 5
11.715723 ABIN1874993 ICC IF IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN2452138 IF IHC (p) ELISA WB Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
11.715723 ABIN2452136 IF IHC (p) WB FITC Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
11.715723 ABIN2452137 IF IHC (p) ELISA WB Biotin Rat IgG2a kappa full length Anmelden zum Anzeigen 4D12 4
11.715723 ABIN948607 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 1-101, full length Anmelden zum Anzeigen 3D7 0
11.715723 ABIN1449279 IF WB Mouse IgG1 Anmelden zum Anzeigen 5B12 0
11.715723 ABIN4304253 ICC IF IHC IHC (p) Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN5079901 ICC IF Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN3032639 IF IHC ELISA WB Rabbit Ig Fraction AA 1-30 Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN3032644 FACS IF IHC ELISA WB Rabbit Ig Fraction AA 1-30 Anmelden zum Anzeigen Polyclonal 0
11.715723 ABIN3032640 FACS IF IHC ELISA WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 0
1 ABIN356734 EIA IF IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 6
1 ABIN650618 FACS IF IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 2
1 ABIN657634 IF IHC (p) WB Rabbit Ig Fraction AA 1-30, N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN318762 IF WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2879035 IF IHC (p) ELISA WB Rabbit IgG AA 1-50 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3187108 ELISA IF IHC WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
Epitop AA 1-30, N-Term
(45), (15), (15), (14), (14), (7), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(345), (152), (109), (9), (8), (7), (7), (6), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(212), (127), (4), (2), (2), (1), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Unkonjugiert
(17), (15), (14), (10), (10), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(276), (142), (137), (123), (113), (110), (66), (51), (40), (39), (10), (10), (6), (2), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Homologie Cow (Bovine),Mouse (Murine),Pig (Porcine),Rat (Rattus)
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This SUMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SUMO1.
Klon RB0629

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung SUMO1 (SUMO1 Antibody Abstract)
Hintergrund Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

Synonyms: SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
NCBI Accession NP_001005781, NP_003343, NP_001005782
UniProt P63165
Pathways M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50,IF: 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Janer, Werner, Takahashi-Fujigasaki, Daret, Fujigasaki, Takada, Duyckaerts, Brice, Dejean, Sittler: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." in: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, 2009

Ji, Degerny, Vintonenko, Deheuninck, Foveau, Leroy, Coll, Tulasne, Baert, Fafeur: "Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation." in: Oncogene, Vol. 26, Issue 3, pp. 395-406, 2007

Bradley, van der Meer, Roodi, Yan, Chandrasekharan, Sun, Mernaugh, Parl: "Carcinogen-induced histone alteration in normal human mammary epithelial cells." in: Carcinogenesis, Vol. 28, Issue 10, pp. 2184-92, 2007

Degerny, Monte, Beaudoin, Jaffray, Portois, Hay, de Launoit, Baert: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, 2005

Yang, Sharrocks: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, 2004

Ling, Sankpal, Robertson, McNally, Karpova, Robertson: "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription." in: Nucleic acids research, Vol. 32, Issue 2, pp. 598-610, 2004

Bailey, OHare: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, 2003

Pountney, Huang, Burns, Haan, Thompson, Blumbergs, Gai: "SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease." in: Experimental neurology, Vol. 184, Issue 1, pp. 436-46, 2003

Ohshima, Shimotohno: "Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 50833-42, 2003

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Flow Cytometry (FACS) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Immunohistochemistry (IHC) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Immunofluorescence (IF) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...