anti-Human SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antikörper für Flow Cytometry

Recommended SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
  • DAP1
  • GMP1
  • OFC10
  • PIC1
  • SENP2
  • SMT3
  • SMT3C
  • SMT3H3
  • UBL1
  • hm:zeh0670
  • wu:fb74c02
  • wu:fd12c02
  • zgc:65934
  • zgc:85634
  • SUMO1
  • dap1
  • gmp1
  • ofc10
  • pic1
  • senp2
  • smt3
  • smt3c
  • sumo-1
  • sumo1
  • ubl1
  • xsumo-1
  • xsumo1
  • ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1
  • ATSUMO1
  • F10M23.180
  • F10M23_180
  • SMALL UBIQUITIN-LIKE MODIFIER 1
  • SUM1
  • SUMO 1
  • small ubiquitin-like modifier 1
  • pigSUMO1
  • SENTRIN
  • SMTP3
  • SUMO-1
  • Smt3C
  • Ubl1
  • small ubiquitin-like modifier 1
  • small ubiquitin-like modifier 1 S homeolog
  • small ubiquitin-related protein 1
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • Sumo1
  • SUMO1
  • sumo1
  • sumo1.S
  • sumo-1
Epitop
AA 1-30, N-Term
45
15
15
14
14
7
7
6
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
345
152
109
9
8
7
7
6
5
3
3
2
2
1
1
1
1
1
Wirt
Kaninchen
212
127
4
2
2
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
17
15
14
10
10
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
276
142
137
123
113
110
66
51
40
39
10
10
6
2
1
Optionen
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Bilder

Produktnummer ABIN1882136
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13.804164 ABIN955007 EIA FACS IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 5
13.804164 ABIN1882137 FACS IF IHC (p) WB Rabbit AA 52-79, Glu67, N-Term Anmelden zum Anzeigen Polyclonal 5
13.804164 ABIN650618 FACS IF IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 2
13.804164 ABIN3032644 FACS IF IHC ELISA WB Rabbit Ig Fraction AA 1-30 Anmelden zum Anzeigen Polyclonal 0
13.804164 ABIN3032640 FACS IF IHC ELISA WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal 0
1 ABIN388027 FACS IHC (p) WB Rabbit Ig Fraction AA 55-86, C-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN2737624 ICC FACS IP IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN3026382 FACS IF IHC WB Mouse IgG1, kappa Anmelden zum Anzeigen SM1-495 0
1 ABIN3026264 FACS IF IHC WB Mouse IgG1, kappa Anmelden zum Anzeigen S1MT-2 0
1 ABIN3026865 FACS IF IHC WB Mouse IgG1, kappa Anmelden zum Anzeigen SPM571 0
1 ABIN3026862 FACS IF IHC (p) WB Mouse IgG1, kappa Anmelden zum Anzeigen SUMO1-1188 0
1 ABIN2628909 ELISA FACS IF IHC WB Rabbit IgG AA 63-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4356783 FACS APC Mouse IgG1 kappa Anmelden zum Anzeigen SM1-495 0
1 ABIN4356826 FACS APC Mouse IgG1 kappa Anmelden zum Anzeigen SUMO1-1188 0
1 ABIN4356800 FACS APC Mouse IgG1 kappa Anmelden zum Anzeigen SPM571 0
1 ABIN2369222 FACS IF IHC ELISA WB Rabbit IgG C-Term, AA 63-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1939464 ELISA FACS ICC IF IHC WB Biotin Rabbit IgG AA 63-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1939466 ELISA FACS ICC IF IHC WB PE Rabbit IgG AA 63-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1939463 ELISA FACS ICC IF IHC WB APC Rabbit IgG AA 63-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1939462 ELISA FACS ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG AA 63-93 Anmelden zum Anzeigen Polyclonal 0

General

Antigen SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
Epitop AA 1-30, N-Term
(45), (15), (15), (14), (14), (7), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(345), (152), (109), (9), (8), (7), (7), (6), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(212), (127), (4), (2), (2), (1), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Unkonjugiert
(17), (15), (14), (10), (10), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(276), (142), (137), (123), (113), (110), (66), (51), (40), (39), (10), (10), (6), (2), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Homologie Cow (Bovine),Mouse (Murine),Pig (Porcine),Rat (Rattus)
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This SUMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SUMO1.
Klon RB0629

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung SUMO1 (SUMO1 Antibody Abstract)
Hintergrund Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

Synonyms: SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
NCBI Accession NP_001005781, NP_003343, NP_001005782
UniProt P63165
Pathways M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50,IF: 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Janer, Werner, Takahashi-Fujigasaki, Daret, Fujigasaki, Takada, Duyckaerts, Brice, Dejean, Sittler: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." in: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, 2009

Ji, Degerny, Vintonenko, Deheuninck, Foveau, Leroy, Coll, Tulasne, Baert, Fafeur: "Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation." in: Oncogene, Vol. 26, Issue 3, pp. 395-406, 2007

Bradley, van der Meer, Roodi, Yan, Chandrasekharan, Sun, Mernaugh, Parl: "Carcinogen-induced histone alteration in normal human mammary epithelial cells." in: Carcinogenesis, Vol. 28, Issue 10, pp. 2184-92, 2007

Degerny, Monte, Beaudoin, Jaffray, Portois, Hay, de Launoit, Baert: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, 2005

Yang, Sharrocks: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, 2004

Ling, Sankpal, Robertson, McNally, Karpova, Robertson: "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription." in: Nucleic acids research, Vol. 32, Issue 2, pp. 598-610, 2004

Bailey, OHare: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, 2003

Pountney, Huang, Burns, Haan, Thompson, Blumbergs, Gai: "SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease." in: Experimental neurology, Vol. 184, Issue 1, pp. 436-46, 2003

Ohshima, Shimotohno: "Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 50833-42, 2003

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Flow Cytometry (FACS) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Immunohistochemistry (IHC) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...
Immunofluorescence (IF) image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (AA 1-30), (N-Term) antibody (ABIN1882136) SUMO1 Antibody (N-term) (ABIN1882136) flow cytometric analysis of Hela cells (right h...