RANKL ELISA Kit

Produktnummer ABIN2042701

Produktdetails RANKL ELISA Kit

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 62.5-4000 pg/mL

Untere Nachweisgrenze: 62.5 pg/mL

Applikation: ELISA

Marke: BioAssay™

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate pre-coated with anti-TNFSF11/RANKL, Mouse
Lyophilized recombinant TNFSF11/RANKL, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Mouse TNFSF11/RANKL in cell culture supernates, serum and plasma (heparin, EDTA).Receptor activator of nuclear factor kappa-B ligand(RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This gene is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu RANKL

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Andere Bezeichnung: TNFSF11ANKL (TNFSF11 Produkte)

Synonyme: CD254 ELISA Kit, ODF ELISA Kit, OPGL ELISA Kit, OPTB2 ELISA Kit, RANKL ELISA Kit, TRANCE ELISA Kit, hRANKL2 ELISA Kit, sOdf ELISA Kit, TNFSF11 ELISA Kit, Ly109l ELISA Kit, OPG ELISA Kit, Trance ELISA Kit, cd254 ELISA Kit, odf ELISA Kit, opgl ELISA Kit, optb2 ELISA Kit, rankl ELISA Kit, sodf ELISA Kit, tnfsf11 ELISA Kit, trance ELISA Kit, TNF superfamily member 11 ELISA Kit, tumor necrosis factor (ligand) superfamily, member 11 ELISA Kit, TNF receptor superfamily member 11b ELISA Kit, TNF superfamily member 11 L homeolog ELISA Kit, TNFSF11 ELISA Kit, Tnfsf11 ELISA Kit, TNFRSF11B ELISA Kit, tnfsf11.L ELISA Kit

Gen-ID: 21943

UniProt: O35235

Pathways: NF-kappaB Signalweg