RANKL ELISA Kit

Produktnummer ABIN2042623

Produktdetails RANKL ELISA Kit

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 93.7-6000 pg/mL

Untere Nachweisgrenze: 93.7 pg/mL

Applikation: ELISA

Marke: BioAssay™

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 5 pg/mL

Bestandteile: 96-well plate pre-coated with anti-OPG, Mouse
Lyophilized recombinant OPG, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Mouse OPG in cell culture supernates, serum and plasma (EDTA).Osteoprotegerin (OPG) is identical to osteoclastogenesis inhibitory factor (OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis.1 OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation.2 Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease.3 It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.4 OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential.5 OPG also plays a role in the vascular system.6

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu RANKL

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Andere Bezeichnung: OPG (TNFSF11 Produkte)

Synonyme: CD254 ELISA Kit, ODF ELISA Kit, OPGL ELISA Kit, OPTB2 ELISA Kit, RANKL ELISA Kit, TRANCE ELISA Kit, hRANKL2 ELISA Kit, sOdf ELISA Kit, TNFSF11 ELISA Kit, Ly109l ELISA Kit, OPG ELISA Kit, Trance ELISA Kit, cd254 ELISA Kit, odf ELISA Kit, opgl ELISA Kit, optb2 ELISA Kit, rankl ELISA Kit, sodf ELISA Kit, tnfsf11 ELISA Kit, trance ELISA Kit, TNF superfamily member 11 ELISA Kit, tumor necrosis factor (ligand) superfamily, member 11 ELISA Kit, TNF receptor superfamily member 11b ELISA Kit, TNF superfamily member 11 L homeolog ELISA Kit, TNFSF11 ELISA Kit, Tnfsf11 ELISA Kit, TNFRSF11B ELISA Kit, tnfsf11.L ELISA Kit

Gen-ID: 18383

UniProt: O08712

Pathways: NF-kappaB Signalweg