anti-Pferd JAK3 Antikörper für Western Blotting

Recommended JAK3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tyrosine-Protein Kinase JAK3 (JAK3) Antikörper
  • JAK-3
  • JAK3_HUMAN
  • JAKL
  • L-JAK
  • LJAK
  • fae
  • wil
  • RATJAK3
  • JAK
  • Janus kinase 3
  • JAK3
  • Jak3
Epitop
Middle Region
19
18
15
15
10
8
7
7
7
5
4
3
3
2
2
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Ratte (Rattus)
117
70
52
2
1
1
1
1
1
Wirt
Kaninchen
87
35
1
Klonalität
Polyklonal
Konjugat
Dieser JAK3 Antikörper ist unkonjugiert
5
5
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
73
50
27
25
19
15
11
9
8
7
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2785645
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.1680543 ABIN2785644 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Tyrosine-Protein Kinase JAK3 (JAK3) Antikörper
Epitop Middle Region
(19), (18), (15), (15), (10), (8), (7), (7), (7), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Ratte (Rattus)
(117), (70), (52), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(87), (35), (1)
Klonalität
Polyklonal
Konjugat Dieser JAK3 Antikörper ist unkonjugiert
(5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(73), (50), (27), (25), (19), (15), (11), (9), (8), (7), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-JAK3 Antikörper

Target Details JAK3 Anwendungsinformationen Handhabung Referenzen für anti-JAK3 Antikörper (ABIN2785645) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN978683.
Sequenz KLLPLDKDYY VVREPGQSPI FWYAPESLSD NIFSRQSDVW SFGVVLYELF
Homologie Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human JAK3
Plasmids, Primers & others

Target Details JAK3

Produktdetails anti-JAK3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-JAK3 Antikörper (ABIN2785645) Bilder zurück nach oben
Antigen
Andere Bezeichnung JAK3 (JAK3 Antibody Abstract)
Hintergrund JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Protein Interaction Partner: Socs5, KIT, IL7R, TYK2, STAT6, STAT3, JAK2, JAK1, IL4R, GTF2B, ERBB3, CDK1, CD81, APOA1, UBC, SOCS3, UHRF2, STAT5A, IKBKG, ALK, SH2B2, TIAF1, INPP5D, PTPN2, STAM2, PRMT5, SOCS1, KHDRBS1, STAM, PTK2B, IRS2, SHB, JAK3, IL2RG, VIL1, FES, CD247, PTPN6, PIK3R1
Protein Size: 1124
Molekulargewicht 125 kDa
Gen-ID 3718
NCBI Accession NM_000215, NP_000206
UniProt P52333
Pathways JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded protein response

Anwendungsinformationen

Produktdetails anti-JAK3 Antikörper Target Details JAK3 Handhabung Referenzen für anti-JAK3 Antikörper (ABIN2785645) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1124 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-JAK3 Antikörper Target Details JAK3 Anwendungsinformationen Referenzen für anti-JAK3 Antikörper (ABIN2785645) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-JAK3 Antikörper (ABIN2785645)

Produktdetails anti-JAK3 Antikörper Target Details JAK3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Cheng, Ross, Frost, Kirken: "Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2271-82, 2008

Bilder

Produktdetails anti-JAK3 Antikörper Target Details JAK3 Anwendungsinformationen Handhabung Referenzen für anti-JAK3 Antikörper (ABIN2785645) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Tyrosine-Protein Kinase JAK3 (JAK3) (Middle Region) antibody (ABIN2785645) WB Suggested Anti-JAK3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...