Rociletinib (CO-1686, AVL-301)

Details zu Produkt Nr. ABIN3220443
Inhibition Assay (InhA), Functional Studies (Func)
Verwendungszweck CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).
Produktmerkmale Target: EGFR inhibitor
Receptor: Mutant EGFR
Reinigung All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Reinheit 99.30 %
Formel C27H28F3N7O3
Löslichkeit DMSO > 10 mM
Hintergrund Tyrosine Kinase/Adaptors
Molekulargewicht 555.55 g/mol
CAS-Nummer 1374640-70-6
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Solid
Lagerung -20 °C
Informationen zur Lagerung For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Haltbarkeit 24 months