EX-527
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- Applikation
- Inhibition (Inh)
- Verwendungszweck
- SIRT1 inhibitor
- Produktmerkmale
- Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.
- Reinheit
- >98 %
- Chemical Name
- 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
- Formel
- C13H13ClN2O
- Permeabilität
- Cell-permeable
- Löslichkeit
- Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Powder
- Lagerung
- -20 °C
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- Hintergrund
- Epigenetics,p53,Protein deacetylase,Stem cells,Neuroscience,Ageing,Neurodegeneration,Posttranslational modification,Chromatin
- Molekulargewicht
- 248.7
- CAS-Nummer
- 49843-98-3
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