anti-Maus Calcium Modulating Ligand Antikörper für Western Blotting

Recommended Calcium Modulating Ligand Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Calcium Modulating Ligand (CAMLG) Antikörper
  • MGC53900
  • CAML
  • AI385748
  • Camlg
  • Caml
  • calcium modulating ligand L homeolog
  • calcium modulating ligand
  • camlg.L
  • CAMLG
  • camlg
  • Caml
  • Camlg
Epitop
N-Term
11
9
7
7
6
4
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen
48
7
7
2
2
2
2
1
1
1
1
Wirt
Kaninchen
36
15
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
51
25
20
10
8
4
4
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2783272
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2186315 ABIN5013278 ICC IHC WB Rabbit IgG AA 1-187 Anmelden zum Anzeigen Polyclonal 0
3.2186315 ABIN4889907 IP WB Guinea Pig Anmelden zum Anzeigen Polyclonal 0
3.2186315 ABIN4889906 IP WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN463633 WB Rabbit IgG AA 36-85 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5515470 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5699421 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN3060709 WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen Calcium Modulating Ligand (CAMLG) Antikörper
Epitop N-Term
(11), (9), (7), (7), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen
(48), (7), (7), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(36), (15), (1)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(51), (25), (20), (10), (8), (4), (4), (2)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974430.
Sequenz LLMNSEQRIN RIMGFHRPGS GAEEESQTKS KQQDSDKLNS LSVPSVSKRV
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%
Produktmerkmale This is a rabbit polyclonal antibody against CAMLG. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CAMLG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung CAMLG (CAMLG Antibody Abstract)
Hintergrund The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alias Symbols: CAML, MGC163197
Protein Interaction Partner: KCNA2, TMUB1, TNFRSF13B, UBC, RNF122, PKHD1, EGFR, PPIB, IER3,
Protein Size: 296
Molekulargewicht 33 kDa
Gen-ID 819
NCBI Accession NM_001745, NP_001736
UniProt P49069
Pathways EGFR Signaling Pathway

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 296 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Nagano, Kitamura, Hujer, Ward, Bram, Hopfer, Tomita, Huang, Miller: "Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling." in: Biochemical and biophysical research communications, Vol. 338, Issue 2, pp. 880-9, 2005

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Calcium Modulating Ligand (CAMLG) (N-Term) antibody (ABIN2783272) WB Suggested Anti-CAMLG Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Posi...