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CAMLG Antikörper

CAMLG Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7257333
  • Target Alle CAMLG Antikörper anzeigen
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Reaktivität
    • 38
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 35
    • 6
    • 1
    Kaninchen
    Klonalität
    • 39
    • 3
    Polyklonal
    Konjugat
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CAMLG Antikörper ist unkonjugiert
    Applikation
    • 32
    • 19
    • 14
    • 5
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CAMLG (NP_001736.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CAMLG Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Andere Bezeichnung
    CAMLG (CAMLG Produkte)
    Synonyme
    MGC53900 antikoerper, CAML antikoerper, AI385748 antikoerper, Camlg antikoerper, Caml antikoerper, calcium modulating ligand L homeolog antikoerper, calcium modulating ligand antikoerper, camlg.L antikoerper, CAMLG antikoerper, camlg antikoerper, Caml antikoerper, Camlg antikoerper
    Hintergrund
    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
    Molekulargewicht

    Observed_MW: 38 kDa

    Calculated_MW: 32 kDa

    Gen-ID
    819
    UniProt
    P49069
    Pathways
    EGFR Signaling Pathway
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