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These data will serve as a foundation for further insight into the cattle ADCY2 gene.
This study demonistrated that adcy2 knockout mice regulate the expression soluble adenylyl cyclase (zeige ADCY10 ELISA Kits) in brain.
In patients receiving capecitabine monotherapy, rs4702484, located in ADCY2 and close to MTRR (zeige MTRR ELISA Kits), was associated with slightly reduced PFS for homozygous wild-type patients (CC 6.2 vs. CT 8.0 months; P=0.018).
Our present study defines an AC2 cAMP signaling compartment that specifically regulates IL-6 (zeige IL6 ELISA Kits) expression in bronchial smooth muscle cells.
AKAP79 (zeige AKAP5 ELISA Kits), PKC, PKA and PDE4 (zeige PDE4A ELISA Kits) participate in a Gq-linked muscarinic receptor (zeige CHRM5 ELISA Kits) and adenylate cyclase 2 cAMP signalling complex.
AGS3 reduced D(2L)DR-mediated sensitization of AC1 and AC2.
A replication of association between two SNPs previously associated with COPD (zeige ARCN1 ELISA Kits) (CHRNA3 (zeige CHRNA3 ELISA Kits)/5 and IREB2 (zeige IREB2 ELISA Kits)), as well as an association with COPD (zeige ARCN1 ELISA Kits) of one locus initially associated with lung function (ADCY2).
Data suggest that SPARCL1, Shp2 (zeige PTPN11 ELISA Kits), MSH2 (zeige MSH2 ELISA Kits), E-cadherin (zeige CDH1 ELISA Kits), p53 (zeige TP53 ELISA Kits), ADCY-2 and MAPK (zeige MAPK1 ELISA Kits) are potential prognostic markers in colorectal cancer.
AC2 and AC4 (zeige ADCY4 ELISA Kits) isoforms, stimulated by GTP binding protein betagamma subunits, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors.
AC2 interacts with RXFP1 (zeige RXFP1 ELISA Kits) through AKAP79 (zeige AKAP5 ELISA Kits), whereas the association with PDE4D3 and PKA depends upon beta-arrestin 2 (zeige ARRB2 ELISA Kits) binding to Ser704.
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
adenylate cyclase 2
, adenylate cyclase 2 (brain)
, adenylate cyclase type 2
, adenylate cyclase type 2-like
, ATP pyrophosphate-lyase 2
, adenylate cyclase type II
, adenylyl cyclase 2
, 3',5'-cyclic AMP synthetase
, adenylate cyclase II
, type II adenylate cyclase
, mutant adenylate cyclase 2