anti-Pferd APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 Antikörper für Western Blotting

Recommended APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) Antikörper
  • apex1
  • MGC76280
  • MGC79645
  • MGC78928
  • APE
  • APE1
  • APEN
  • APEX
  • APX
  • HAP1
  • REF1
  • Apex
  • REF-1
  • BAP1
  • apex1a
  • hm:zehn1532
  • wu:fc13d11
  • zgc:66204
  • Ref-1
  • apurinic/apyrimidinic endodeoxyribonuclease 1
  • APEX nuclease (multifunctional DNA repair enzyme) 1
  • APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog
  • DNA-(apurinic or apyrimidinic site) lyase
  • apurinic/apyrimidinic endonuclease 1
  • APEX1
  • apex1
  • apex1.L
  • CNG03640
  • CNH01280
  • nth
  • Spirs_4119
  • Palpr_0103
  • Apex1
Epitop
Middle Region
25
12
11
9
5
5
5
5
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
213
84
79
16
15
14
12
11
8
6
5
5
4
2
1
1
1
1
1
1
Wirt
Kaninchen
156
50
18
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
6
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
197
85
77
62
46
22
16
13
13
10
8
8
4
2
2
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen

Bilder

Produktnummer ABIN2787519
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
7.726376 ABIN2779778 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
7 ABIN202230 IHC IHC (p) WB Rabbit IgG AA 79-128 Anmelden zum Anzeigen Polyclonal 0
4.726376 ABIN2779916 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
4.726376 ABIN2779917 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
4.726376 ABIN5515369 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
4 ABIN202227 WB Rabbit IgG AA 21-70 Anmelden zum Anzeigen Polyclonal 0
4 ABIN575493 WB Rabbit AA 215-264 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2616816 IHC IHC (p) WB Rabbit IgG AA 177-191 Anmelden zum Anzeigen Polyclonal 0

General

Antigen APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) Antikörper
Epitop Middle Region
(25), (12), (11), (9), (5), (5), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(213), (84), (79), (16), (15), (14), (12), (11), (8), (6), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(156), (50), (18)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(6), (6), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(197), (85), (77), (62), (46), (22), (16), (13), (13), (10), (8), (8), (4), (2), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973301.
Sequenz HEEIDLRNPK GNKKNAGFTP QERQGFGELL QAVPLADSFR HLYPNTPYAY
Homologie Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against APEX1. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human APEX1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung APEX1 (APEX1 Antibody Abstract)
Hintergrund Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein.
Alias Symbols: APE, APE1, APEN, APEX, APX, HAP1, REF-1, REF1
Protein Interaction Partner: GADD45A, UBC, RPA3, RPA2, RPA1, rev, CCDC124, RIC8A, PABPC1, TWF2, XPOT, HNRNPUL1, ARIH2, PAPSS2, NAE1, PSMG1, TXNRD1, TXN, TCEB1, LGALS1, HNRNPK, CAPNS1, SRPK2, SRPK1, MUTYH, HMGA1, HMGA2, GZMK, GZMA, YBX1, EP300, ASCL2, STAT3, SNRPD1, SFPQ, APP, UBE2I,
Protein Size: 318
Molekulargewicht 35 kDa
Gen-ID 328
NCBI Accession NM_001641, NP_001632
UniProt P27695
Pathways DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 318 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) (Middle Region) antibody (ABIN2787519) WB Suggested Anti-APEX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive...
Western Blotting (WB) image for anti-APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) (Middle Region) antibody (ABIN2787519) WB Suggested Anti-APEX1 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 Posi...