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Human Interleukin 8 Protein expressed in Escherichia coli (E. coli) - ABIN1305113
Matsushima, Oppenheim: Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF. in Cytokine 1991
Show all 2 Pubmed References
Human Interleukin 8 Protein expressed in Escherichia coli (E. coli) - ABIN413549
Reeves, Williamson, ONeill, Greally, McElvaney: Nebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosis. in American journal of respiratory and critical care medicine 2011
Human Interleukin 8 Protein expressed in Escherichia coli (E. coli) - ABIN624491
Leyh, Seitz, Dürselen, Schaumburger, Ignatius, Grifka, Grässel: Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes. in Arthritis research & therapy 2015
IL-8 production was significantly enhanced following treatment with both IL-17A (zeige IL17A Proteine) and CSE, while treatment with either IL-17A (zeige IL17A Proteine) or CSE alone caused only a slight increase in IL-8 production.
The expression of the inflammatory cytokines interleukin (IL)6 (zeige IL6 Proteine) and IL8 was significantly increased in endometriotic and cocultured cells compared with healthy ECs.
Work identified IL-8 as a positive regulator of homotypic CIC formation via enhancing intercellular adhesion.
V2O5 induction of CXCL8 and CXCL11 (zeige CXCL11 Proteine) chemokines may lead to the appearance and perpetuation of an inflammatory reaction into the dermal tissue. Further studies are required to evaluate dermal integrity and manifestations in subjects occupationally exposed, or living in polluted areas.
Study findings point out that PAR2 (zeige F2RL1 Proteine) could play an essential role in gastroesophageal reflux disease (GERD) pathogenesis - even repeated short-term exposure to weakly acidic conditions lead to the upregulation of PAR2 (zeige F2RL1 Proteine) and subsequent activation of the intense IL-8 release in the esophageal mucosa and initiation of mucosal immune response in GERD.
Given that IL-8, MIP-1beta (zeige CCL4 Proteine), and MCP-1 (zeige CCL2 Proteine) are chemokines that play important roles in recruitment of immunocompetent cells for immune defense and tumor cell clearance, the observed lower levels of these markers with increasing PM2.5 exposure may provide insight into the mechanism by which DEE promotes lung cancer.
These results suggested that stemness induction in SKOV3 cells by macrophages co-cultured with SKOV3-derived OCSLCs involved IL-8/STAT3 (zeige STAT3 Proteine) signaling.
IL-8-251T>A (rs4073) Polymorphism is associated with gastric Cancer.
expression level of CXCL8 had a positive relationship with recurrence probability in Acute myeloid leukemia (zeige BCL11A Proteine).
These data were in close agreement with the reduced cell migration and colony formation. Results from the present study suggested that reparixin and SCH527123 may be promising therapeutic agents for the treatment of pancreatic cancer by inhibiting the IL8/CXCR1 (zeige CXCR1 Proteine)/2 signaling cascade.
Molecular characterization of the bovine IER3 (zeige IER3 Proteine) gene: Down-regulation of IL-8 by blocking NF-kappaB (zeige NFKB1 Proteine) activity mediated by IER3 (zeige IER3 Proteine) overexpression in MDBK cells infected with bovine viral diarrhea virus-1.
STA3 (zeige ARHGEF3 Proteine) facilitates TLR4 (zeige TLR4 Proteine)-dependent IL-6 (zeige IL6 Proteine) and IL-8 production via IL-6 (zeige IL6 Proteine) receptor-positive feedback in endometrial cells.
As a pilot study, the present results revealed that identified SNPs in IL8 and TLR4 (zeige TLR4 Proteine) genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 (zeige TLR4 Proteine) gene may be a potential candidate for such disease.
Blood levels of cortisol, immunoglobulin G, and IL-8 in relationship to genetics and the incidence of bovine respiratory complex disease are reported.
Genetic variation at the IL8 locus explains a proportion of the inter-breed and inter-individual variation in immunity between neonatal calves which is likely to influence their resistance to infection.
In response to C. abortus infection, both ovine and bovine turbinate cells produce CXCL8 mRNA and protein late in the bacterial developmental cycle.
Studied association of IL8 -105G/A with mastitis somatic cell score in Chinese Holstein dairy cows. Results suggest genotype GG may be a useful genetic marker for mastitis resistance selection and breeding in Chinese Holstein dairy cows.
Data implicate a complex cascade of events during luteolysis, involving Il8 signaling, neutrophil recruitment, and immune cell action within the corpus luteum.
Cadmium exposure induced pulmonary inflammation and increased lung interleukin 8 secretion.
Exposure to follicular fluid transiently increased the transcript levels of IL8 and PTGS2 (zeige PTGS2 Proteine), and decreased the expression of SOD2 (zeige SOD2 Proteine), GPX3 (zeige GPX3 Proteine), DAB2 (zeige DAB2 Proteine), and NR3C1 (zeige NR3C1 Proteine). TNF (zeige TNF Proteine) and IL6 (zeige IL6 Proteine) levels were also decreased while those of NAMPT (zeige NAMPT Proteine) were unaffected.
This study evaluated the subcellular localization and other functions of TGEV nsp7 protein through analysis of its effects on cell growth, cell cycle progression, interleukin 8 (IL-8) expression, and NF-kappaB (zeige NFKB1 Proteine) activation.
The JNK (zeige MAPK8 Proteine)-activated AP-1 (zeige JUN Proteine) subunit c-Jun (zeige JUN Proteine) was critical for the up-regulation of IL-8 expression by PRRSV
These results suggest that porcine circovirus 2 induces IL-8 secretion via the TLR2/MyD88 (zeige MYD88 Proteine)/NF-kappaB (zeige NFKB1 Proteine) signalling pathway.
Facilitated degradation of the RGS16 (zeige RGS16 Proteine) by porcine circovirus type 2 ORF3 further enhances NFkappaB translocation into the nucleus through the ERK1/2 signalling pathway and increased IL-6 (zeige IL6 Proteine) and IL-8 mRNA transcripts.
Suggest that the interplay between TGFbeta (zeige TGFB1 Proteine)-2 and LPS (zeige IRF6 Proteine) regulates the levels of IL-8 in the immature newborn intestine.
Data suggest that MSK1 (zeige RPS6KA5 Proteine) and MSK2 are the major CREB (zeige CREB1 Proteine) kinases in fibroblast-like synoviocytes from rheumatoid arthritis patients stimulated with lysophosphatidic acid and that phosphorylation of CREB1 (zeige CREB1 Proteine) at Ser (zeige SIGLEC1 Proteine)-133 plays a significant role in IL-8 production.
Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (zeige IL1B Proteine), IL-8 and TNF-alpha (zeige TNF Proteine) in porcine alveolar macrophages.
local expression of IL-1beta (zeige IL1B Proteine) and IL-8 in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
In swine, IL-8, TNF-ALPHA (zeige TNF Proteine), INOS (zeige NOS2 Proteine) AND MIP-1BETA (zeige CCL4 Proteine) were increased during mechanical ventilation in a time-related fashion.
Classical swine fever virus NS2 protein promotes interleukin-8 expression.
Stress decreased IL-8 gene expression in both CeA (zeige CEACAM3 Proteine) lesioned and non-lesioned animals. But, CeA (zeige CEACAM3 Proteine) lesions increased the tissue expression of IL-8 mRNA prior to and after stress exposure.
gene expression and epistasis analysis indicated that CXCL8(IL-8) was a functional target of vitamin D3-mediated HSPC (zeige PSMA7 Proteine) regulation. Together, these findings highlight the relevance of developmental 1,25(OH)D3 availability for definitive hematopoiesis and suggest potential therapeutic utility in HSPC (zeige PSMA7 Proteine) expansion
Targeted expression of the human oncogene (zeige RAB1A Proteine) KRASG12V in zebrafish gills induces inflammation and cxcl8-l1 expression.
Data show that both Cxcl8-l1 and Cxcl8-l2 are required for larva survival upon Salmonella Typhimurium infection.
results explain how early H2O2 signal regulates neutrophil recruitment at all phases, directly via Lyn (zeige LYN Proteine) oxidation or indirectly by modulating cxcl8 gene expression
The data identify HOXC9 (zeige HOXC9 Proteine) as an endothelial cell active transcriptional repressor promoting the resting, antiangiogenic endothelial cell phenotype in an interleukin 8-dependent manner
Here, we report the characterisation of genes encoding the zebrafish Cxcl8, Cxcr1 (zeige CXCR1 Proteine) and Cxcr2 (zeige CXCR2 Proteine)
At the 2-wk time point, interleukin 8 gene expression was comparable in intervertebral discs injected with chondrocytes in controls, whereas its expression in IVDs injected with saline increased 50-fold
Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1 (zeige CCL2 Proteine)) and interleukin-8 (IL-8) decreased significantly in Dachengqi decoction treatment group.
The JNK (zeige MAPK8 Proteine) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha (zeige TNF Proteine) expression in alveolar macrophages, but the injury-stimulated IL-8 expression may be regulated by other signaling pathways.
IL-8 and IL-1ra (zeige IL1RN Proteine) showed correlation with the severity of colitis. These observations should significantly further understandings on the role of neutrophils and monocytes in the immunopathogenesis of ulcerative colitis
Results suggested that chemokine (zeige CCL1 Proteine) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
Mapped six genes (EIF4G3 (zeige EIF4G3 Proteine), HSP90 (zeige HSP90AB1 Proteine), RBBP6 (zeige RBBP6 Proteine), IL8, TERT (zeige TERT Proteine), and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization.
This study examined effects of in vitro exposure to solutions of hay (zeige GTF2H5 Proteine) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
These results suggest that MMP-1 (zeige MMP1 Proteine) and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.
Duck IL-8 is good immunostimulant to enhance the immune efficiency of avian influenza vaccine in ducks.
IL-8 homologue has been cloned and identified; the chemokine CXC domain, which contained Glu-Leu-Arg motif and four cysteine residues, was well conserved
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
T-cell chemotactic factor
, alveolar macrophage chemotactic factor I
, beta endothelial cell-derived neutrophil activating peptide
, beta-thromboglobulin-like protein
, chemokine (C-X-C motif) ligand 8
, granulocyte chemotactic protein 1
, lung giant cell carcinoma-derived chemotactic protein
, lymphocyte derived neutrophil activating peptide
, monocyte-derived neutrophil chemotactic factor
, monocyte-derived neutrophil-activating peptide
, neutrophil-activating peptide 1
, small inducible cytokine subfamily B, member 8
, tumor necrosis factor-induced gene 1
, C-X-C motif chemokine 8
, neutrophil activating peptide 1
, alveolar macrophage-derived chemotactic factor-I
, interleukin 8
, neutrophil attractant/activation protein 1
, neutrophil attractant/activation protein-1
, permeability factor 1
, Interleukin-8-like protein
, Neutrophil attractant protein 1
, neutrophil attractant protein-1
, uncharacterized protein LOC100036815