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anti-Human ARL2 Antikörper:
anti-Mouse (Murine) ARL2 Antikörper:
anti-Rat (Rattus) ARL2 Antikörper:
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Human Polyclonal ARL2 Primary Antibody für IHC, IHC (p) - ABIN4281598
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Polyclonal ARL2 Primary Antibody für ELISA, WB - ABIN249610
Clark, Moore, Krasinskas, Way, Battey, Tamkun, Kahn: Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes. in Proceedings of the National Academy of Sciences of the United States of America 1993
High ARL2 expression is associated with Osteosarcoma.
conclude that the TBCD (zeige TBCD Antikörper)*ARL2*beta-tubulin (zeige TUBB Antikörper) complex represents a functional intermediate in the beta-tubulin (zeige TUBB Antikörper) folding pathway whose activity is regulated by the cycling of nucleotides on ARL2
Results identified ARL2 and TBCD (zeige TBCD Antikörper), as important in tubulin (zeige TUBB Antikörper) folding and microtubule dynamics. Both ARL2 and TBCD (zeige TBCD Antikörper) also localize to centrosomes. A growing body of evidence also has found roles for ARL2 inside mitochondria, as a regulator of mitochondrial fusion, and in the traffic of farnesylated cargos between membranes and specifically to cilia and photoreceptor cells. [review]
In conclusion, our study revealed that miR (zeige MLXIP Antikörper)-214 acts as a tumor suppressor via inhibiting proliferation, migration and invasion of cervical cancer cells through targeting ARL2, and that both miR (zeige MLXIP Antikörper)-214 and ARL2 may serve as prognostic or therapeutic targets for cervical cancer.
Novel Biochemical and Structural Insights into the Interaction of Myristoylated Cargo with Unc119 (zeige UNC119 Antikörper) Protein and Their Release by Arl2/3.
We hypothesize that ARL2 plays essential roles inside mitochondria along with other cellular functions, at least in part to provide coupling of regulation between these essential cell processes.
MiR (zeige MLXIP Antikörper)-195 regulates cell apoptosis in a context-dependent manner through directly targeting ARL2.
The G proteins Arl2 acts in a GTP (zeige AK3 Antikörper)-dependent manner as allosteric release factors for farnesylated cargo.
a novel function of miR-16 (zeige GDE1 Antikörper) targeting ARL2 in modulating proliferation and cell cycle progression.
Data show that bovine and human TBCD (zeige TBCD Antikörper) have functionally identical roles in tubulin (zeige TUBB Antikörper) heterodimer assembly, and that the inability of human TBCD (zeige TBCD Antikörper) to disrupt microtubule integrity can be overcome by siRNA-mediated suppression of expression of Arl2.
two pathways in mitochondria, one affecting ATP levels that is independent of ELMOD2 (zeige ELMOD2 Antikörper) and the other leading to mitochondrial fusion involving MFN2 (zeige MFN2 Antikörper) that does involve ELMOD2 (zeige ELMOD2 Antikörper)
Studies indicate that Arf-like proteins ARL2 and ARL3 are not substrates for N-myristoyl transferase.
Arl2, a small GTPase (zeige RACGAP1 Antikörper), has an important regulator of breast tumor cell aggressivity, both in vitro and in vivo
Arf-like protein 2 interaction with PDEdelta is dependent on GTP (zeige AK3 Antikörper), and the binding of PDEdelta substantially stabilizes GTP binding (zeige RND2 Antikörper); data suggests that Arl2/3 are specific regulators of PDEdelta
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes.
ADP-ribosylation factor-like 2
, ADP-ribosylation factor-like protein 2
, ADP-ribosylation-like 2
, arf-like protein 2