ARL2 Antikörper

Produktnummer ABIN7111380

Produktdetails anti-ARL2 Antikörper

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ADP-ribosylation factor-like 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ARL2

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Andere Bezeichnung: ARL2 (ARL2 Produkte)

Synonyme: arfl2 antikoerper, MGC75676 antikoerper, ARFL2 antikoerper, 2610009M23Rik antikoerper, AI115441 antikoerper, AW553335 antikoerper, ADP ribosylation factor like GTPase 2 antikoerper, ADP-ribosylation factor-like 2 antikoerper, ADP-ribosylation factor like GTPase 2 antikoerper, arl2 antikoerper, ARL2 antikoerper, Arl2 antikoerper

Hintergrund: Synonyms: Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Molekulargewicht: 21-25 kDa

Gen-ID: 402

UniProt: P36404

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location