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Parkinson's disease

Parkinson's disease is one of the most well known neurodegenerative diseases. It is a chronic, progressive neurodegenerative disease characterized by both motor and nonmotor features. The disease has a significant clinical impact on patients, families, and caregivers through its progressive degenerative effects on mobility and muscle control.(1) An estimated 7 to 10 million people worldwide suffer from Parkinson's disease. antibodies-online offers a hand-picked number of antibodies, ELISA kits, recombinant proteins, as well as other tools for Parkinson's research.

Here you will find a list of important antibodies, reagents, kits, and other tools you need for your research in the field of Parkinson's disease, as well as some more additional resources on the topic.

Important Targets in Parkinson's Research

The following targets are directly related to research on Parkinson's disease. Search Antibodies, Kits, Reagents and other products. Click on a gene to see the available products.

Autosomal recessive and X-linked genes involved in Parkinson’s disease(2)

Autosomal dominant genes involved in Parkinson’s disease(2)

alpha-Synuclein (SNCA) / PARK1

α-Synuclein is a presynaptic neuronal protein that is linked genetically and neuropathologically to Parkinson's disease (PD).(3) We offer a variety of reliable mono- and polyclonal SNCA antibodies.

Produkt
Reaktivität
Klonalität
Applikation
Kat. Nr.
Menge
ReaktivitätCow, Dog, Human, Mouse, Primate, Rat
KlonalitätPolyclonal
ApplikationWB
Kat. Nr.ABIN2477391
Menge0.1 mL
ReaktivitätHuman
KlonalitätPolyclonal
ApplikationIF, WB
Kat. Nr.ABIN6148190
Menge100 μL
ReaktivitätHuman
KlonalitätMonoclonal
ApplikationIHC, ELISA, WB
Kat. Nr.ABIN1724652
Menge100 μL
ReaktivitätMammalian
KlonalitätMonoclonal
ApplikationELISA, IF, IHC, WB
Kat. Nr.ABIN536927
Menge100 μL

See all alpha-Synuclein Antibodies

LRRK2 / PARK8

As a promising target for neuroprotection strategies in PD, in vitro and in vivo models that accurately demonstrate LRRK2's function relevant to neurodegeneration will aide in the identification of molecules with the highest chance of success in the clinic.(4)

Produkt
Reaktivität
Klonalität
Applikation
Kat. Nr.
Menge
ReaktivitätHuman, Mouse
KlonalitätPolyclonal
ApplikationIF, ELISA, WB
Kat. Nr.ABIN3031610
Menge0.4 mL
ReaktivitätHuman, Mouse
KlonalitätPolyclonal
ApplikationIHC, ELISA, WB
Kat. Nr.ABIN3031607
Menge0.4 mL
ReaktivitätHuman
KlonalitätPolyclonal
ApplikationIHC, ELISA, WB
Kat. Nr.ABIN3028794
Menge0.4 mL

DJ-1 / PARK7

The DJ-1 gene is a causative gene for familial PD (park7) and also an oncogene. DJ-1 has various functions, including transcriptional regulation, antioxidative stress reaction, and chaperone, protease, and mitochondrial regulation.(5)

Produkt
Reaktivität
Klonalität
Applikation
Kat. Nr.
Menge
ReaktivitätHuman
KlonalitätMonoclonal
ApplikationELISA, WB
Kat. Nr.ABIN532936
Menge100 μL

See all DJ-1 Antibodies

Featured ELISA Kits

Here you will find a range of reliable ELISA kits with PubMed references for a number of PD related targets, which allow a quick and easy detection of proteins in biological samples. Click on the links to find more information.

Produkt
Reaktivität
Detection Method
Kat. Nr.
Menge
ReaktivitätHuman
Detection MethodqPCR
(Pre-coated)
Kat. Nr.ABIN6386150
Menge96 tests
ReaktivitätHuman
Detection MethodqPCR
(Pre-coated)
Kat. Nr.ABIN6386133
Menge96 tests
ReaktivitätMouse
Detection MethodColorimetric
(Pre-coated)
Kat. Nr.ABIN415770
Menge96 tests
ReaktivitätMouse
Detection MethodColorimetric
(Pre-coated)
Kat. Nr.ABIN819944
Menge96 tests

References

(1) DeMaagd G, Philip A. Parkinson's Disease and Its Management: Part 1: Disease Entity, Risk Factors, Pathophysiology, Clinical Presentation, and Diagnosis. P T. 2015 Aug;40(8):504-32. PMID: 26236139; PMCID: PMC4517533.

(2) Emamzadeh, F. N., & Surguchov, A. (2018). Parkinson's Disease: Biomarkers, Treatment, and Risk Factors. Frontiers in neuroscience, 12, 612. doi:10.3389/fnins.2018.00612

(3) Stefanis L. α-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med. 2012 Feb;2(2):a009399. doi: 10.1101/cshperspect.a009399. PMID: 22355802; PMCID: PMC3281589.

(4) Webber PJ, West AB. LRRK2 in Parkinson's disease: function in cells and neurodegeneration. FEBS J. 2009 Nov;276(22):6436-44. doi: 10.1111/j.1742-4658.2009.07342.x.

(5) Ariga H, Takahashi-Niki K, Kato I, Maita H, Niki T, Iguchi-Ariga SM. Neuroprotective function of DJ-1 in Parkinson's disease. Oxid Med Cell Longev. 2013;2013:683920. doi: 10.1155/2013/683920. Epub 2013 May 16. PMID: 23766857; PMCID: PMC3671546.