Parkin Produkte
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Kategorien
The precise function of this gene is unknown\; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008].
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Ausgewählte Parkin Kategorien
Parkin Antikörper
High quality antibodies with extensive validation data.
Parkin ELISA Kits
Reliable ELISA kits for a wide range of species.
Parkin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Parkin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (6)
Kat. Nr.
ABIN390366
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN562106
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (10)
Kat. Nr.
ABIN3021179
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Parkin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969157
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6958411
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381401
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Parkin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124320
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314008
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314010
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Parkin Produkten
: "PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation." in: Redox biology, Vol. 26, pp. 101254, (2019) (PubMed).: "Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases." in: Frontiers in pharmacology, Vol. 7, pp. 100, (2016) (PubMed).
: "Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy." in: The journals of gerontology. Series A, Biological sciences and medical sciences, (2016) (PubMed).
: "Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative DNA damage." in: Histology and histopathology, Vol. 31, Issue 10, pp. 1143-59, (2016) (PubMed).
: "In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146083, (2016) (PubMed).
: "Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro." in: Cell and tissue research, Vol. 364, Issue 3, pp. 465-74, (2016) (PubMed).
: "ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts." in: Scientific reports, Vol. 6, pp. 24700, (2016) (PubMed).
: "Expression pattern of parkin isoforms in lung adenocarcinomas." in: Tumour biology, (2015) (PubMed).
: "Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance." in: Molecular neurobiology, Vol. 53, Issue 9, pp. 6270-6287, (2015) (PubMed).
: "Neuroprotective effects of extract of Acanthopanax senticosus harms on SH-SY5Y cells overexpressing wild-type or A53T mutant ?-synuclein." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 5, pp. 704-11, (2014) (PubMed).
Synonyme und alternative Namen zu Parkin
parkin (park), parkin RBR E3 ubiquitin protein ligase (PRKN), parkin RBR E3 ubiquitin protein ligase (Prkn), parkin RBR E3 ubiquitin protein ligase (prkn), parkin (CpipJ_CPIJ014867), Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2), AR-JP, CG10523, Dmel\\CG10523, Dpark, dpk, LPRS2, Park, PARK2, PDJ, pdr-1, PRKN, Prkn, SD01679, si:ch211-123f21.1, zgc:112390Bezeichner auf Proteinebene für Parkin
- CG10523-PB
- CG10523-PC
- D-parkin
- dparkin
- park-PB
- park-PC
- E3 ubiquitin-protein ligase parkin
- Parkinson disease (autosomal recessive, juvenile) 2, parkin
- parkinson juvenile disease protein 2
- parkin variant SV5DEL
- parkin
- parkin protein
- parkinson protein 2, E3 ubiquitin protein ligase (parkin)
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