MC1 Receptor Produkte
(Melanocortin 1 Receptor (MC1R))
Kategorien
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008].
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Ausgewählte MC1 Receptor Kategorien
MC1 Receptor Antikörper
High quality antibodies with extensive validation data.
MC1 Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
MC1 Receptor Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MC1 Receptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7159233
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN686287
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC, IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN2856574
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MC1 Receptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6233295
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6233294
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MC1 Receptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310505
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310504
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3099289
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MC1 Receptor Produkten
: "Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4396467, (2018) (PubMed).: "Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying." in: BioMed research international, Vol. 2015, pp. 651048, (2016) (PubMed).
: "Increased corticotropin-releasing hormone (CRH) expression in cutaneous lupus lesions." in: Lupus, Vol. 24, Issue 8, pp. 854-61, (2015) (PubMed).
Synonyme und alternative Namen zu MC1 Receptor
melanocortin 1 receptor (MC1R), melanocortin 1 receptor (Mc1r), melanocortin 1 receptor (mc1r), melanocortin 1 receptor (mc1r_par1), melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) (MC1R), CMM5, e, MC1-R, mc1r, MC1R, MSH-R, MSHR, Mshra, SHEP2, Tob, TUBB3Bezeichner auf Proteinebene für MC1 Receptor
- MC1-R
- melanocyte-stimulating hormone receptor
- melanotropin receptor
- MSH-R
- extension recessive yellow
- melanocortin receptor 1
- melanocortin-1 receptor
- tobacco darkening
- BDF3
- alpha melanocyte stimulating hormone receptor
- melanocortin 1-receptor
- melanocyte stimulating hormone receptor
- melanocortin 1 receptor
- Melanotropin receptor
- Melanocortin receptor 1
- Melanocyte-stimulating hormone receptor
- tubulin, beta 3 class III
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