MCC Produkte
(Mutated in Colorectal Cancers (MCC))
Kategorien
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte MCC Kategorien
MCC Antikörper
High quality antibodies with extensive validation data.
MCC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MCC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (4)
Kat. Nr.
ABIN950122
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, RNAi
Validierungen
- (4)
Kat. Nr.
ABIN561756
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7148294
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene MCC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310523
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310525
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3091956
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MCC Produkten
: "'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival." in: Immunology, Vol. 143, Issue 4, pp. 618-30, (2014) (PubMed).: "CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway." in: Blood, Vol. 114, Issue 3, pp. 580-8, (2009) (PubMed).
: "Loss of heterozygosity of APC and MCC genes in oral squamous cell carcinomas in Taiwan." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 26, Issue 7, pp. 322-6, (1997) (PubMed).
: "MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase." in: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10341-6, (1996) (PubMed).
: "Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer." in: International journal of cancer. Journal international du cancer, Vol. 55, Issue 4, pp. 598-603, (1993) (PubMed).
: "MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer." in: Oncogene, Vol. 6, Issue 10, pp. 1881-6, (1991) (PubMed).
: "Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers." in: Science (New York, N.Y.), Vol. 251, Issue 4999, pp. 1366-70, (1991) (PubMed).
Synonyme und alternative Namen zu MCC
mutated in colorectal cancers (MCC), mutated in colorectal cancers (mcc), mutated in colorectal cancers (Mcc), D18Ertd451e, E330037C19, MCC, mcc1, MCC1, RGD1561988Bezeichner auf Proteinebene für MCC
- mutated in colorectal cancers
- colorectal mutant cancer protein
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