MCM8 Produkte
(Minichromosome Maintenance Deficient 8 (MCM8))
Kategorien
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte MCM8 Kategorien
MCM8 Antikörper
High quality antibodies with extensive validation data.
MCM8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MCM8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB, IHC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN309831
Menge
25 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN529702
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN6737804
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MCM8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6211736
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MCM8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1310565
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1990369
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137049
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MCM8 Produkten
: "RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination." in: Molecular cell, Vol. 66, Issue 5, pp. 622-634.e8, (2017) (PubMed).: "The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination." in: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1632-44, (2013) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues." in: Human pathology, Vol. 40, Issue 1, pp. 41-9, (2008) (PubMed).
Synonyme und alternative Namen zu MCM8
minichromosome maintenance 8 homologous recombination repair factor (MCM8), minichromosome maintenance 8 homologous recombination repair factor (Mcm8), minichromosome maintenance 8 homologous recombination repair factor L homeolog (mcm8.L), 5730432L01Rik, C20orf154, dJ967N21.5Bezeichner auf Proteinebene für MCM8
- DNA helicase MCM8
- DNA replication licensing factor MCM8
- MCM8 minichromosome maintenance deficient 8
- REC homolog
- minichromosome maintenance 8
- minichromosome maintenance deficient 8
- Minichromosome maintenance 8
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