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MCU Produkte

(Mitochondrial Calcium Uniporter (MCU))
This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].

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Ausgewählte MCU Kategorien

MCU Antikörper

High quality antibodies with extensive validation data.

MCU ELISA Kits

Reliable ELISA kits for a wide range of species.

MCU Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MCU Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN7268549
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7146314
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation ELISA, WB, IHC
Validierungen
  • (2)
Kat. Nr. ABIN6260526
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MCU ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Competition ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1744117
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1745336
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1742896
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MCU Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310583
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3093728
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3122086
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MCU Produkten

Yan, Li, Yan, Zhao, Liu, Liu: "Effects of luteolin on regulatory proteins and enzymes for myocyte calcium circulation in hypothermic preserved rat heart." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1433-1441, (2018) (PubMed).

Lee, Min, Kim, Song, Lim, Kim, Shin, Kang, Kang, Youn, Lee, An, Park, Lim, Kim, Kim, Park, Kim, Wang, Kim, Eom: "Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter." in: EMBO reports, Vol. 16, Issue 10, pp. 1318-33, (2015) (PubMed).

Stauch, Purnell, Fox: "Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability." in: Journal of proteome research, Vol. 13, Issue 5, pp. 2620-36, (2014) (PubMed).

Kovács-Bogdán, Sancak, Kamer, Plovanich, Jambhekar, Huber, Myre, Blower, Mootha: "Reconstitution of the mitochondrial calcium uniporter in yeast." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. 8985-90, (2014) (PubMed).

Arruda, Pers, Parlakgül, Güney, Inouye, Hotamisligil: "Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity." in: Nature medicine, Vol. 20, Issue 12, pp. 1427-35, (2014) (PubMed).

Logan, Szabadkai, Sharpe, Parry, Torelli, Childs, Kriek, Phadke, Johnson, Roberts, Bonthron, Pysden, Whyte, Munteanu, Foley, Wheway, Szymanska, Natarajan, Abdelhamed, Morgan, Roper, Santen, Niks et al.: "Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. ..." in: Nature genetics, Vol. 46, Issue 2, pp. 188-93, (2014) (PubMed).

Samanta, Douglas, Parekh: "Mitochondrial calcium uniporter MCU supports cytoplasmic Ca2+ oscillations, store-operated Ca2+ entry and Ca2+-dependent gene expression in response to receptor stimulation." in: PLoS ONE, Vol. 9, Issue 7, pp. e101188, (2014) (PubMed).

Qiu, Tan, Hagenston, Martel, Kneisel, Skehel, Wyllie, Bading, Hardingham: "Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals." in: Nature communications, Vol. 4, pp. 2034, (2013) (PubMed).

Pan, Liu, Nguyen, Liu, Sun, Teng, Fergusson, Rovira, Allen, Springer, Aponte, Gucek, Balaban, Murphy, Finkel: "The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter." in: Nature cell biology, Vol. 15, Issue 12, pp. 1464-72, (2013) (PubMed).

Baughman, Perocchi, Girgis, Plovanich, Belcher-Timme, Sancak, Bao, Strittmatter, Goldberger, Bogorad, Koteliansky, Mootha: "Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter." in: Nature, Vol. 476, Issue 7360, pp. 341-5, (2011) (PubMed).

Synonyme und alternative Namen zu MCU

mitochondrial calcium uniporter (MCU), mitochondrial calcium uniporter (Mcu), 2010012O16Rik, AV064928, C10orf42, CCDC109A, Ccdc109a, D130073L02Rik, Gm64

Bezeichner auf Proteinebene für MCU

  • calcium uniporter protein, mitochondrial
  • coiled-coil domain-containing protein 109A
  • coiled-coil domain containing 109A
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