GBA Produkte
(Glucosidase, Beta, Acid (GBA))
Kategorien
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
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Ausgewählte GBA Kategorien
GBA Antikörper
High quality antibodies with extensive validation data.
GBA ELISA Kits
Reliable ELISA kits for a wide range of species.
GBA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GBA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (5)
- (6)
Kat. Nr.
ABIN561009
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7434968
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7074062
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GBA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967044
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6999571
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956132
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GBA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123107
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354861
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354863
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GBA Produkten
: "LRRK2 modifies α-syn pathology and spread in mouse models and human neurons." in: Acta neuropathologica, Vol. 137, Issue 6, pp. 961-980, (2019) (PubMed).: "Fetal gene therapy for neurodegenerative disease of infants." in: Nature medicine, Vol. 24, Issue 9, pp. 1317-1323, (2018) (PubMed).
: "Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling." in: Human molecular genetics, Vol. 24, Issue 5, pp. 1280-94, (2015) (PubMed).
: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." in: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).
: "Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS." in: Orphanet journal of rare diseases, Vol. 9, pp. 86, (2014) (PubMed).
: "Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease." in: Kidney international, Vol. 86, Issue 1, pp. 58-66, (2014) (PubMed).
: "Gaucher disease paradigm: from ERAD to comorbidity." in: Human mutation, Vol. 33, Issue 10, pp. 1398-407, (2012) (PubMed).
: "Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant." in: Blood cells, molecules & diseases, Vol. 46, Issue 1, pp. 4-10, (2011) (PubMed).
: "Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome." in: Blood, Vol. 114, Issue 15, pp. 3181-90, (2009) (PubMed).
Synonyme und alternative Namen zu GBA
glucosylceramidase beta (GBA), beta glucosidase 25 (BGLU25), beta-glucosidase (PSPTO_3318), beta-glucosidase (bglX), Beta-glucosidase (bglA4), glucosidase, beta, acid (Gba), glucosylceramidase beta (Gba), glucosylceramidase (LOC100399524), beta-glucosidase (bglA.2), bglX-2 (bglX-2), glucosidase, beta, acid (GBA), BETA-GLUCOSIDASE, betaGC, beta glucosidase 25, GBA1, GC, GCase, GCB, GLUC, PSPTO3318, PSPTO4290, T12J13.8, T12J13_8Bezeichner auf Proteinebene für GBA
- D-glucosyl-N-acylsphingosine glucohydrolase
- acid beta-glucosidase
- alglucerase
- beta-glucocerebrosidase
- glucosylceramidase
- imiglucerase
- lysosomal glucocerebrosidase
- beta-glucosidase
- Beta-glucosidase
- acid beta glucosidase
- glucocerebrosidase
- glucosidase, beta; acid
- glucosidase, beta, acid
- glucosylceramidase-like
- glucosidase, beta; acid (includes glucosylceramidase)
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