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anti-Human NME1 Antikörper:
anti-Mouse (Murine) NME1 Antikörper:
anti-Rat (Rattus) NME1 Antikörper:
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Human Monoclonal NME1 Primary Antibody für WB - ABIN1882270
Gilles, Presecan, Vonica, Lascu: Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. in The Journal of biological chemistry 1991
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Human Monoclonal NME1 Primary Antibody für IF, WB - ABIN967855
MacDonald, De la Rosa, Benedict, Freije, Krutsch, Steeg: A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential. in The Journal of biological chemistry 1994
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Chicken Monoclonal NME1 Primary Antibody für IF, IP - ABIN967854
Postel, Ferrone: Nucleoside diphosphate kinase enzyme activity of NM23-H2/PuF is not required for its DNA binding and in vitro transcriptional functions. in The Journal of biological chemistry 1994
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Human Monoclonal NME1 Primary Antibody für ICC, FACS - ABIN969317
Treharne, Giles Best, Mehta: Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis. in FEBS letters 2009
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Human Monoclonal NME1 Primary Antibody für IF, IHC (p) - ABIN562004
Liu, Xing, Huang, Jiang, He, Xu, Yuan, Zhou, Yang, Zhuang: Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis. in Toxicology and applied pharmacology 2009
elevated NDKA was associated with severe characteristics of adenomas (>/=3 lesions, size >/= 1 cm or villous component). Setting specificity to 85%, NDKA showed a sensitivity of 30.19% and 29.82% for advanced adenomas and advanced neoplasia, respectively.
This study suggested that EGFR (zeige EGFR Antikörper) was an important predictive factor for the prognosis of the post-operative patients with colorectal carcinoma TNM (zeige ODZ1 Antikörper) stage I-II, and nm23 is important for predicting the prognosis of the patients with stage III-IV; it is better that EGFR (zeige EGFR Antikörper) and nm23 are as predictor of combination.
Results demonstrate that nm23 plays a vital role in decidualization in mice and humans and that nm23 gene expression is hormonally regulated.
NM23 might be an indicator of good prognosis in patients with breast cancer, although further researches need to be performed to confirm the prognostic value of NM23. [Meta-analysis; review]
The data presented suggest an important role for cytoplasmic IRF6 (zeige IRF6 Antikörper) in regulating the availability or localization of the NME1/2 complex and thus the dynamic behavior of epithelia during lip/palate development.
High NME1 expression is associated with well tumor differentiation in Digestive System Neoplasms
Hepatitis C Virus E1 protein expression and HCV infection induces pro-metastatic effect on cancer cells which is simultaneous to Nm23-H1 transcriptional down-regulation and Nm23-H1 protein degradation.
Meta-analysis showed that low expression of nm23-H1 is associated with poorer prognosis in patients with nasopharyngeal carcinoma, suggesting that it is a prognostic factor and potential biomarker for survival in nasopharyngeal carcinoma.
Nm23-H1 nuclear localized mainly in the G2/M phase and the nuclear Nm23-H1 promoted A549 cell proliferation in vitro.
Differential regulation of NM23-H1 may corroborate/abrogate EMT (zeige ITK Antikörper) depending on the nature of stress, tumor microenvironment and cellular context.
Deletion of NME1 reduced total NDPK activity and exacerbated activation of the stress-related MAPK (zeige MAPK1 Antikörper), JNK (zeige MAPK8 Antikörper), in the liver in response to paraquat. NDPK activity protects cells from acute oxidative stress by inhibiting activation of JNK (zeige MAPK8 Antikörper) in mammal models.
EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase
data suggested that NME1 acts as a switcher or reprogramming factor which involves in oligodentrocyte versus neuron cell fate specification in vitro
NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma.
NME1 controls annexin IV (zeige ANXA4 Antikörper) and EF-1Balpha amounts by post-translational mechanisms.
data show a critical role for NM23 isoforms in limiting mutagenesis and suppressing UVR-induced melanomagenesis
GAPDH (zeige GAPDH Antikörper) and NDPK are genetic modifiers of murine DDC (zeige DDC Antikörper)-induced liver injury
The work provides a rare instance of nm23-1/NDPKA physiological functions in the mammary glands and reveals its implication as a modulator factor of proliferation and apoptosis in this tissue.
Ha-ras oncogene (zeige RAB1A Antikörper) regulates morphogenesis, tumorigenesis, and metastasis through suppressing nm23 expression and modulation of immune cell function
Data suggested that nm23-M1/NDPK A was involved in the process of blastocyst implantation.
NDPKB is required for VEGF (zeige VEGFA Antikörper)-induced angiogenesis and contributes to the correct localization of VEGF receptor (zeige FLT1 Antikörper) type 2 and VE-cadherin (zeige CDH5 Antikörper) at the endothelial adherens junctions.
Data show that NDPK B knockdown embryo results in a severe decrease in cardiac contractility.
NDPK-A exists in a functional cellular complex with AMPK (zeige PRKAA2 Antikörper) and CFTR (zeige CFTR Antikörper) in airway epithelia, and NDPK-A catalytic function is required for the AMPK (zeige PRKAA2 Antikörper)-dependent regulation of CFTR (zeige CFTR Antikörper)
The physical interaction between phytochrome A in the Pfr form and NDPK-In results in a significant increase in the kinase activity of NDPK-In. The results presented in this work indicate that NDPK-In may function as a protein kinase regulated by light.
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
NDP kinase A
, granzyme A-activated DNase
, metastasis inhibition factor nm23
, non-metastatic cells 1, protein (NM23A) expressed in
, nucleoside diphosphate kinase A
, tumor metastatic process-associated protein
, NDK A
, expressed in non-metastatic cells 1 protein
, expressed in non-metastatic cells 1, protein
, metastasis inhibition factor NM23
, nucleoside-diphosphate kinase 1
, nucleotide diphosphate kinase
, NDP kinase beta
, expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase)
, expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase)
, nucloside diphosphate kinase
, non-metastatic cells 2, protein (NM23B) expressed in
, non-metastatic cells 2b.1, protein (NM23B) expressed in
, nucleoside diphosphate kinase-Z1
, NME1-NME2 readthrough transcript
, expressed in non-metastatic cells 1
, NDK A2
, NDP kinase A2
, NM23/nucleoside diphosphate kinase A2
, ndk a1
, nucleoside diphosphate kinase A2
, NDK A 1
, NDK A 2
, NDK NBR-A
, NDK NBR-B
, NDP kinase A 1
, NDP kinase A 2
, nucleoside diphosphate kinase A 1
, nucleoside diphosphate kinase A 2
, nucleoside diphosphate kinase NBR-A
, nucleoside diphosphate kinase NBR-B
, nucleoside-diphosphate kinase NBR-A
, nucleoside-diphosphate kinase NBR-B
, NDK A1
, NDP kinase A1
, NM23/nucleoside diphosphate kinase A1
, ndk a2
, nucleoside diphosphate kinase A1
, NDP kinase I
, nucleoside diphosphate kinase 1
, nucleoside diphosphate kinase I
, NDK I
, NDPK I
, Nucleoside diphosphate kinase I