anti-Human BIRC5 Antikörper für Western Blotting

Recommended BIRC5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Baculoviral IAP Repeat-Containing 5 (BIRC5) Antikörper
  • API4
  • EPR-1
  • AAC-11
  • Api4
  • TIAP
  • survivin40
  • AP14
  • baculoviral IAP repeat containing 5
  • baculoviral IAP repeat-containing 5-like
  • baculoviral IAP repeat-containing 5
  • BIRC5
  • LOC696283
  • Birc5
Epitop
AA 121-142, C-Term
14
10
9
5
4
3
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
88
36
16
Wirt
Kaninchen
68
32
4
Klonalität
Polyklonal
Konjugat
Dieser BIRC5 Antikörper ist unkonjugiert
8
3
2
1
1
1
1
1
Applikation
Western Blotting (WB)
79
42
26
21
14
14
6
5
4
3
2
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN3043195
$ 240.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0797327 ABIN396525 WB Mouse IgG2a kappa AA 1-101 Anmelden zum Anzeigen 5B10 5
3.0797327 ABIN3042792 IHC (p) ELISA WB Rabbit IgG AA 1-142 Anmelden zum Anzeigen Polyclonal 4
3.0797327 ABIN1845166 ELISA FACS IF/ICC IHC WB Mouse IgG1 Anmelden zum Anzeigen 0
3.0797327 ABIN4880564 ELISA FACS ICC IHC WB Mouse IgG1 Anmelden zum Anzeigen 1H5 0
3.0797327 ABIN5518813 ELISA WB Rabbit IgG AA 1-142 Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN4900855 CyTOF FACS IHC SimWes WB Goat IgG Anmelden zum Anzeigen Polyclonal 2
3.0797327 ABIN1875407 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN559893 IF IP RNAi ELISA WB Mouse IgG2a kappa AA 1-100, partial Anmelden zum Anzeigen 5B10 2
3.0797327 ABIN969504 ICC FACS IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 1H5 0
3.0797327 ABIN947570 IF IP WB Rabbit AA 1-142, full length Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN513406 IF PLA WB Rabbit AA 1-142, full length Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN2465183 ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN5611620 EIA IF IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN2723214 FACS IF WB Mouse IgG1 Anmelden zum Anzeigen 2D9 0
3.0797327 ABIN5649814 ELISA FACS IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 1H5 0
3.0797327 ABIN2989836 IF/ICC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN5648990 ELISA IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN1107626 WB Mouse IgG1 Anmelden zum Anzeigen 2H5H2 3
3.0797327 ABIN513405 IF WB Mouse AA 1-142, full length Anmelden zum Anzeigen Polyclonal 0
3.0797327 ABIN5649815 ELISA WB Mouse IgG1 Anmelden zum Anzeigen 2H5H2 0

General

Antigen Baculoviral IAP Repeat-Containing 5 (BIRC5) Antikörper
Epitop AA 121-142, C-Term
(14), (10), (9), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(88), (36), (16)
Wirt Kaninchen
(68), (32), (4)
Klonalität
Polyklonal
Konjugat Dieser BIRC5 Antikörper ist unkonjugiert
(8), (3), (2), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(79), (42), (26), (21), (14), (14), (6), (5), (4), (3), (2), (2), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-BIRC5 Antikörper

Target Details BIRC5 Anwendungsinformationen Handhabung Referenzen für anti-BIRC5 Antikörper (ABIN3043195) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Human.
Sequenz KKEFEETAKK VRRAIEQLAA MD
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Human.
Gene Name: baculoviral IAP repeat containing 5
Protein Name: Baculoviral IAP repeat-containing protein 5
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human survivin(121-142aa KKEFEETAKKVRRAIEQLAAMD).
Isotyp IgG
Plasmids, Primers & others

Target Details BIRC5

Produktdetails anti-BIRC5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-BIRC5 Antikörper (ABIN3043195) Bilder zurück nach oben
Antigen
Andere Bezeichnung BIRC5 (BIRC5 Antibody Abstract)
Hintergrund Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis(IAP) family. The survivin gene contains 4 exons. The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Synonyms: API4 antibody|Apoptosis Inhibitor 4 antibody|Apoptosis inhibitor survivin antibody|Apoptosis inhibitor4 antibody|Baculoviral IAP repeat containing 5 antibody|Baculoviral IAP repeat containing protein 5 antibody|Baculoviral IAP repeat-containing protein 5 antibody|BIRC 5 antibody|BIRC5 antibody|EPR 1 antibody|IAP4 antibody|Survivin variant 3 alpha antibody|SVV antibody|TIAP antibody
UniProt O15392
Pathways Apoptose, Zellzyklus

Anwendungsinformationen

Produktdetails anti-BIRC5 Antikörper Target Details BIRC5 Handhabung Referenzen für anti-BIRC5 Antikörper (ABIN3043195) Bilder zurück nach oben
Applikations-hinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-BIRC5 Antikörper Target Details BIRC5 Anwendungsinformationen Referenzen für anti-BIRC5 Antikörper (ABIN3043195) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungs-mittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months

Referenzen für anti-BIRC5 Antikörper (ABIN3043195)

Produktdetails anti-BIRC5 Antikörper Target Details BIRC5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Li, Zhao, Lu, Li, Yang, Wu, Liu: "Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation." in: PLoS ONE, Vol. 9, Issue 4, pp. e95912, 2014

Zhang, Lu, Hou, Hu, Wang: "The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells." in: Tumour biology, Vol. 35, Issue 6, pp. 5401-7, 2014

Hao, Huang, Liao, Zhu, Liu, Hao, Liu, Zhang, Feng, Ning, Li, Li: "The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice." in: Fitoterapia, Vol. 86, pp. 84-91, 2013

Li, Zhang, Fang, Yan, Zhao, Feng, Ma, Ye: "Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1." in: Biochemical and biophysical research communications, Vol. 434, Issue 4, pp. 809-14, 2013

Cai, Liu, Zhao, Wan, Hu, Zhou, Chen: "Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy." in: International journal of ophthalmology, Vol. 5, Issue 3, pp. 293-6, 2012

Shan, Zhang, Geng, Zhou, Chen, Nie, Guo, Li, Liu, Guo, Wei, Chen: "Expression of survivin and human telomerase reverse transcriptase in extramammary Paget's disease." in: Journal of cutaneous pathology, Vol. 37, Issue 6, pp. 635-40, 2010

Bilder

Produktdetails anti-BIRC5 Antikörper Target Details BIRC5 Anwendungsinformationen Handhabung Referenzen für anti-BIRC5 Antikörper (ABIN3043195) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 121-142), (C-Term) antibody (ABIN3043195) Anti-survivin antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell...