anti-Human BID Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended BID Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
BH3 Interacting Domain Death Agonist (BID) Antikörper
  • FP497
  • 2700049M22Rik
  • AI875481
  • AU022477
  • BID
  • bid
  • si:ch211-238n5.6
  • fp497
  • xbid
  • DKFZp469E066
  • BH3 interacting domain death agonist
  • BH3 interacting domain death agonist S homeolog
  • BID
  • Bid
  • bida
  • bid.S
  • bid
Reaktivität
Human, Maus, Ratte (Rattus)
325
171
75
9
5
3
2
Wirt
Kaninchen
301
97
21
9
Klonalität
Polyklonal
Konjugat
Dieser BID Antikörper ist unkonjugiert
24
22
14
9
8
7
4
4
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
359
185
164
87
50
41
36
24
16
13
11
11
3
2
1
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN4284618
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.362932 ABIN4284621 IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 3
12.362932 ABIN4284615 IHC IHC (fro) IHC (p) IP WB Rabbit Anmelden zum Anzeigen Polyclonal 4
12.362932 ABIN4284613 IHC IHC (fro) IHC (p) IP WB Rabbit Anmelden zum Anzeigen Polyclonal 1
12.362932 ABIN153045 IHC (p) IHC WB Rabbit AA 60-120 Anmelden zum Anzeigen Polyclonal 2
12.362932 ABIN738441 IF (p) IHC (p) Rabbit IgG AA 142-192 Anmelden zum Anzeigen Polyclonal 1
12.362932 ABIN343922 ELISA IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
12.362932 ABIN121851 IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
12.362932 ABIN4284620 ELISA IF IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
12.362932 ABIN4906603 IF IHC (p) WB Mouse IgG1 kappa Anmelden zum Anzeigen 1519CT649-18-47 0
1 ABIN358089 EIA IHC (p) WB Rabbit Ig Fraction pSer65 Anmelden zum Anzeigen Polyclonal 5
1 ABIN389523 IHC (p) WB Rabbit Ig Fraction pSer65 Anmelden zum Anzeigen Polyclonal 5
1 ABIN3042321 ICC IHC (p) WB Rabbit IgG AA 1-195 Anmelden zum Anzeigen Polyclonal 0
1 ABIN388099 IHC (p) WB Rabbit Ig Fraction AA 68-103, BH3 Domain Anmelden zum Anzeigen Polyclonal 3
1 ABIN356816 EIA IHC (p) WB Rabbit Ig Fraction BH3 Domain Anmelden zum Anzeigen Polyclonal 4
1 ABIN957168 IHC IHC (fro) IHC (p) IP WB Rabbit AA 28-50 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2888649 ELISA IHC IHC (p) WB Rabbit IgG AA 44-93 Anmelden zum Anzeigen Polyclonal 0
1 ABIN127033 IHC (p) IP WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN573988 IHC IHC (p) WB Rat IgG1 Anmelden zum Anzeigen 1H11 0
1 ABIN343921 ELISA IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN957167 IHC IHC (fro) IHC (p) IP WB Rabbit AA 1-55 Anmelden zum Anzeigen Polyclonal 0

General

Antigen BH3 Interacting Domain Death Agonist (BID) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(325), (171), (75), (9), (5), (3), (2)
Wirt Kaninchen
(301), (97), (21), (9)
Klonalität
Polyklonal
Konjugat Dieser BID Antikörper ist unkonjugiert
(24), (22), (14), (9), (8), (7), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(359), (185), (164), (87), (50), (41), (36), (24), (16), (13), (11), (11), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-BID Antikörper

Target Details BID Anwendungsinformationen Handhabung Referenzen für anti-BID Antikörper (ABIN4284618) Bilder
Spezifität Full-length Bid is known to undergo cleavage/truncation (reviewed in Yin, 2006). Bid was initially found to be cleaved and activated by capspase-8 following death receptor activation. The term "Bid" was first used to described the caspase-8 cleaved/truncated C-terminal Bid. Bid can be also cleaved by other proteases such as Granzyme B, calpains and cathepsin. The C-terminal portion is considered to be the active Bid moiety. This active form can translocate from the cytosol to the mitochondria. Therefore, the appearance of Bid in the mitochondria is considered to be an indication of active Bid. However, it should also be noted that Bid has been shown to translocate to the mitochondria without cleavage in some model systems. The proteolytic cleavage of Bid usually occurs in the unstructured loop region between the alpha 2 and alpha 3 helices, which is between amino acids (aa) 41 and 79 of Bid. For example, the caspase-8/3 cleavage site is at 60 (human) and 59 (mouse). It should be noted that after cleavage, the smaller N-terminal portion of Bid is not necessarily separated from the larger C-terminal portion. The exact size of the C-terminal cleavage products depends on the Bid cleavage sites, generally 11-15 kDa C-truncated cleavage forms are generated. Shorter C-terminal Bid cleavage products may result from protease cleavage that involves both caspases and other proteases. Full length Bid is quite stable, but cleaved/truncated forms may have a short half-life (less than 1.5 h) and degrade rapidly. Therefore, a time course may be useful when detecting Bid cleavage fragments.
Reinigung Unpurified
Immunogen A synthetic peptide corresponding to amino acids 28-50 (CSDNSFRRELDALGHELPVLAPQ) of human Bid (also known as Bid, isoform 2) was used as immunogen, GenBank no. NP_001187.1. Human Bid is a 195 amino acid protein.

Target Details BID

Produktdetails anti-BID Antikörper Anwendungsinformationen Handhabung Referenzen für anti-BID Antikörper (ABIN4284618) Bilder zurück nach oben
Antigen
Andere Bezeichnung BID (BID Antibody Abstract)
Hintergrund Gene Symbol: BID
Gen-ID 637
NCBI Accession NP_001187
Pathways Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-BID Antikörper Target Details BID Handhabung Referenzen für anti-BID Antikörper (ABIN4284618) Bilder zurück nach oben
Applikations-hinweise Western Blot 1:1000-1:2000, Immunohistochemistry, Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-BID Antikörper Target Details BID Anwendungsinformationen Referenzen für anti-BID Antikörper (ABIN4284618) Bilder zurück nach oben
Format Liquid
Buffer Whole antisera
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-BID Antikörper (ABIN4284618)

Produktdetails anti-BID Antikörper Target Details BID Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Krajewska, Rosenthal, Mikolajczyk, Stennicke, Wiesenthal, Mai, Naito, Salvesen, Reed, Fiskum, Krajewski: "Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation." in: Experimental neurology, Vol. 189, Issue 2, pp. 261-79, 2004 Weitere Details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Bilder

Produktdetails anti-BID Antikörper Target Details BID Anwendungsinformationen Handhabung Referenzen für anti-BID Antikörper (ABIN4284618) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BH3 Interacting Domain Death Agonist (BID) antibody (ABIN4284618) Immunohistochemistry-Paraffin: Bid Antibody [ABIN42846188] - Staining of Mouse Embryo...
Western Blotting (WB) image for anti-BH3 Interacting Domain Death Agonist (BID) antibody (ABIN4284618) Western Blot: Bid Antibody [ABIN42846188] - Analysis of Bid using this antibody. this...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BH3 Interacting Domain Death Agonist (BID) antibody (ABIN4284618) Immunohistochemistry-Paraffin: Bid Antibody [ABIN42846188] - Staining of Human tissue...