CD73 Antikörper

Produktnummer ABIN969322

Produktdetails anti-CD73 Antikörper

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD73 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of NT5E expressed in E. coli.

Klon: 1D7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-CD73 Antikörper (ABIN969322)

Zhou, Zhi, Zhou, Chen, Zhao, Shao, Ou, Yin: "Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).

Wink, Braganhol, Tamajusuku, Casali, Karl, Barreto-Chaves, Sarkis, Battastini: "Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions." in: Neurochemistry international, Vol. 43, Issue 7, pp. 621-8, (2003) (PubMed).

Details zu CD73

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Andere Bezeichnung: NT5E (NT5E Produkte)

Synonyme: CALJA antikoerper, CD73 antikoerper, E5NT antikoerper, NT antikoerper, NT5 antikoerper, NTE antikoerper, eN antikoerper, eNT antikoerper, zgc:63784 antikoerper, NT5E antikoerper, MGC114869 antikoerper, PSPTO2277 antikoerper, 2210401F01Rik antikoerper, AI447961 antikoerper, Nt5 antikoerper, 5'-nucleotidase ecto antikoerper, 5'-nucleotidase, ecto (CD73) antikoerper, 5'-nucleotidase antikoerper, 5' nucleotidase, ecto antikoerper, NT5E antikoerper, nt5e antikoerper, nt5e.S antikoerper, PSPTO_2277 antikoerper, CBU_1233 antikoerper, MCA1322 antikoerper, Nt5e antikoerper

Hintergrund:

Description: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.

Aliases: eN, NT5, CD73

Molekulargewicht: 70 kDa

Gen-ID: 4907

HGNC: 4907

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process